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An electrochemical aptasensor for Δ9-tetrahydrocannabinol detection in saliva on a microfluidic platform

Author(s): Kékedy-Nagy L; Perry JM; Little SR; Llorens OY; Shih SCC;

We present a novel "on-off", cost-effective, rapid electrochemical aptasensor combined with a microfluidics cartridge system for the detection of ?9-THC (?9-tetrahydrocannabinol) in human saliva via differential pulse voltammetry. The assay relied on the competitive binding between the ?9-THC and a soluble redox indicator methylene blue, using an aptamer ...

Article GUID: 36549107


Detection of Fusobacterium nucleatum subspecies in the saliva of pre-colorectal cancer patients, using tandem mass spectrometry

Author(s): Morsi H; Golizeh M; Brosseau N; Janati AI; Emami E; Ndao M; Tran SD;

Objective: Rising evidence links Fusobacterium nucleatum (F. nucleatum) with its four subspecies; nucleatum, polymorphum, animalis, and vincentii, with the development of colorectal cancer (CRC) and its precursor colorectal adenoma (CRA). This study aims to optimize a technique for and explore the capability of matrix-assisted laser-desorption ionization- ...

Article GUID: 34929558


A threshold LC-MS/MS method for 92 analytes in oral fluid collected with the Quantisal® device

Author(s): Desharnais B; Lajoie MJ; Laquerre J; Mireault P; Skinner CD;

A study of impaired driving rates in the province of Québec is currently planned following the legalization of recreational cannabis in Canada. Oral fluid (OF) samples are to be collected with a Quantisal® device and sent to the laboratory for analysis. In order to prepare for this project, a qualitative decision point analysis method monitoring for the p ...

Article GUID: 33035929


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