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Prevalence of insomnia and use of sleep aids among adults in Canada

Author(s): Morin CM; Vézina-Im LA; Chen SJ; Ivers H; Carney CE; Chaput JP; Dang-Vu TT; Davidson JR; Belleville G; Lorrain D; Horn O; Robillard R;

Objectives: To estimate the prevalence of insomnia and the use of sleep aids among Canadian adults. Methods: Data were derived from a phone interview conducted (April to October 2023) with a stratified, population-based sample of 4037 adults (57.6 % females; mean age 50.6 ± 18.4; range 18-102 ye ...

Article GUID: 39369578


Transcriptional and secretome analysis of Rasamsonia emersonii lytic polysaccharide mono-oxygenases

Author(s): Raheja Y; Singh V; Kumar N; Agrawal D; Sharma G; Di Falco M; Tsang A; Chadha BS;

The current study is the first to describe the temporal and differential transcriptional expression of two lytic polysaccharide monooxygenase (LPMO) genes of Rasamsonia emersonii in response to various carbon sources. The mass spectrometry based secretome analysis of carbohydrate active enzymes (CAZymes) expression in response to different carbon sources ...

Article GUID: 39167166


Metabolomics 2023 workshop report: moving toward consensus on best QA/QC practices in LC-MS-based untargeted metabolomics

Author(s): Mosley JD; Dunn WB; Kuligowski J; Lewis MR; Monge ME; Ulmer Holland C; Vuckovic D; Zanetti KA; Schock TB;

Introduction: During the Metabolomics 2023 conference, the Metabolomics Quality Assurance and Quality Control Consortium (mQACC) presented a QA/QC workshop for LC-MS-based untargeted metabolomics. Objectives: The Best Practices Working Group disseminated recent findings from community forums and ...

Article GUID: 38980450


Interactive effects of alcohol and cannabis quantities in the prediction of same-day negative consequences among young adults

Author(s): Wardell JD; Coelho SG; Farrelly KN; Fox N; Cunningham JA; O' Connor RM; Hendershot CS;

Background: Simultaneous alcohol and cannabis use is common, but observational studies examining negative consequences of simultaneous use have rarely considered dose-related interactions between alcohol and cannabis. This study examined interactions between quantities of cannabis and alcohol con ...

Article GUID: 38575530


A thermostable and inhibitor resistant β-glucosidase from Rasamsonia emersonii for efficient hydrolysis of lignocellulosics biomass

Author(s): Raheja Y; Singh V; Sharma G; Tsang A; Chadha BS;

The present study reports a highly thermostable ß-glucosidase (GH3) from Rasamsonia emersonii that was heterologously expressed in Pichia pastoris. Extracellular ß-glucosidase was purified to homogeneity using single step affinity chromatography with molecular weight of ~ 110 kDa. Intriguingly, the purified enzyme displayed high tolerance to inhibitors ma ...

Article GUID: 38470501


Variation the in relationship between urban tree canopy and air temperature reduction under a range of daily weather conditions

Author(s): Locke DH; Baker M; Alonzo M; Yang Y; Ziter CD; Murphy-Dunning C; O' Neil-Dunne JPM;

Mitigating heat is a vital ecosystem service of trees, particularly with climate change. Land surface temperature measures captured at a single time of day (in the morning) dominate the urban heat island literature. Less is known about how local tree canopy and impervious surface regulate air temperature throughout the day, and/or across many days with va ...

Article GUID: 38352758


Weighty words: exploring terminology about weight among samples of physicians, obesity specialists, and the general public

Author(s): Wilson OWA; Nutter S; Russell-Mayhew S; Ellard JH; Alberga AS; MacInnis CC;

Background: The words used to refer to weight and individuals with large bodies can be used to reinforce weight stigma. Given that most previous research has examined preferred terminology within homogenous groups, this research sought to examine terminology preferences across populations. Methods: This paper reports on data gathered with the general pub ...

Article GUID: 38131299


Metabolomics 2022 workshop report: state of QA/QC best practices in LC-MS-based untargeted metabolomics, informed through mQACC community engagement initiatives

Author(s): Dunn WB; Kuligowski J; Lewis M; Mosley JD; Schock T; Ulmer Holland C; Zanetti KA; Vuckovic D;

Introduction: The Metabolomics Quality Assurance and Quality Control Consortium (mQACC) organized a workshop during the Metabolomics 2022 conference. Objectives: The goal of the workshop was to disseminate recent findings from mQACC community-engagement efforts and to solicit feedback about a li ...

Article GUID: 37940740


CRISPR/Cas9 mediated gene editing of transcription factor ACE1 for enhanced cellulase production in thermophilic fungus Rasamsonia emersonii

Author(s): Singh V; Raheja Y; Basotra N; Sharma G; Tsang A; Chadha BS;

Background: The filamentous fungus Rasamsonia emersonii has immense potential to produce biorefinery relevant thermostable cellulase and hemicellulase enzymes using lignocellulosic biomass. Previously in our lab, a hyper-cellulase producing strain of R. emersonii was developed through classical breeding and system biology approaches. ACE1, a pivotal trans ...

Article GUID: 37658430


Identification of the driving factors of microplastic load and morphology in estuaries for improving monitoring and management strategies: A global meta-analysis

Author(s): Feng Q; An C; Chen Z; Lee K; Wang Z;

Estuaries are one of the primary pathways for transferring microplastics (MPs) from the land to the ocean. A comprehensive understanding of the load, morphological characteristics, driving factors, and potential risks of MPs in estuaries is imperative to inform reliable management in this critical transboundary area. Extracted from 135 publications, a glo ...

Article GUID: 37336353


Non-Reproductive Sexual Behavior in Wild White-Thighed Colobus Monkeys (Colobus vellerosus)

Author(s): Teichroeb JA; Fox SA; Samartino S; Wikberg EC; Sicotte P;

Rare behaviors are often missing from published papers, hampering phylogenetic analyses. Here, we report, for the first time, masturbation and same-sex sexual behavior (SSB) in both male and female black-and-white colobus monkeys. We recorded these behaviors during 32 months of observation (1573 h of focal animal sampling) on Colobus vellerosus collected ...

Article GUID: 36849676


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