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Examining Dimensionality and Item-Quality of the Eating Disorder Examination Questionnaire in Individuals With Eating Disorders Using Item Response Theory Analysis

Author(s): Dufour R; Steiger H; Booij L;

Objective: The Eating Disorder Examination Questionnaire (EDE-Q) is a widely-used measure of eating-disorder symptoms. However, inconsistent replication of the subscale structure raises concern about validity. To provide a rigorous test of the EDE-Q's dimensionality and item-quality, we applied modern and classical test theory approaches to data obtai ...

Article GUID: 39548958


Predictive heating load management and energy flexibility analysis in residential sector using an archetype gray-box modeling approach: Application to an experimental house in Québec

Author(s): Abtahi M; Athienitis A; Delcroix B;

This paper presents a methodology to develop archetype gray-box models and use them in an economic model-based predictive control algorithm to simulate optimal heating load management in response to a newly-introduced static time-of-use tariff for Québec's residential sector, rate Flex-D. The methodology is evaluated through a case study, wherein in s ...

Article GUID: 39507415


The β2-adrenergic biased agonist nebivolol inhibits the development of Th17 and the response of memory Th17 cells in an NF-κB-dependent manner

Author(s): Hajiaghayi M; Gholizadeh F; Han E; Little SR; Rahbari N; Ardila I; Lopez Naranjo C; Tehranimeh K; Shih SCC; Darlington PJ;

Introduction: Adrenergic receptors regulate metabolic, cardiovascular, and immunological functions in response to the sympathetic nervous system. The effect of ß2-adrenergic receptor (AR) as a high expression receptor on different subpopulations of T cells is complex and varies depending on the t ...

Article GUID: 39445009


Bismuth-Tin Core-Shell Particles From Liquid Metals: A Novel, Highly Efficient Photothermal Material that Combines Broadband Light Absorption with Effective Light-to-Heat Conversion

Author(s): Seyda D; Dincer O; Ince D; Cugunlular M; Unalan HE; Çinar Aygün S;

This study presents a pioneering investigation of hybrid bismuth-tin (BiSn) liquid metal particles for photothermal applications. It is shown that the intrinsic core-shell structure of liquid metal particles can be instrumentalized to combine the broadband absorption characteristics of defect-rich nano-oxides and the high light-to-heat conversion efficien ...

Article GUID: 39375946


Challenges and Approaches in the Study of Neural Entrainment

Author(s): Duecker K; Doelling KB; Breska A; Coffey EBJ; Sivarao DV; Zoefel B;

When exposed to rhythmic stimulation, the human brain displays rhythmic activity across sensory modalities and regions. Given the ubiquity of this phenomenon, how sensory rhythms are transformed into neural rhythms remains surprisingly inconclusive. An influential model posits that endogenous oscillations entrain to external rhythms, thereby encoding envi ...

Article GUID: 39358026


Hypothalamic-pituitary-adrenal axis function in the offspring of parents with bipolar disorder and the impact of the family environment: A pilot study of the Reducing Unwanted Stress in the Home (RUSH) prevention program

Author(s): Ping EY; Herriot H; Iacono V; Serravalle L; Ellenbogen MA;

Background: The home environment of offspring of parents with bipolar disorder (OBD) has been characterized by high levels of stress and disorganization, which may impact development of the hypothalamic-pituitary-adrenal (HPA) axis and their subsequent risk for affective disorders. The present study examined the effects of a family-based preventative inte ...

Article GUID: 39357242


pH-Responsive Degradable Electro-Spun Nanofibers Crosslinked via Boronic Ester Chemistry for Smart Wound Dressings

Author(s): Casillas-Popova SN; Lokuge ND; Andrade-Gagnon B; Chowdhury FR; Skinner CD; Findlay BL; Oh JK;

Recent advances in the treatment of chronic wounds have focused on the development of effective strategies for cutting-edge wound dressings based on nanostructured materials, particularly biocompatible poly(vinyl alcohol) (PVA)-based electro-spun (e-spun) nanofibers. However, PVA nanofibers need ...

Article GUID: 38989606


Design, Synthesis, and Acid-Responsive Disassembly of Shell-Sheddable Block Copolymer Labeled with Benzaldehyde Acetal Junction

Author(s): Andrade-Gagnon B; Casillas-Popova SN; Jazani AM; Oh JK;

Smart nanoassemblies degradable through the cleavage of acid-labile linkages have attracted significant attention because of their biological relevance found in tumor tissues. Despite their high potential to achieve controlled/enhanced drug release, a systematic understanding of structural factors that affect their pH sensitivity remains challenging, part ...

Article GUID: 38499007


Candida albicans exhibits heterogeneous and adaptive cytoprotective responses to anti-fungal compounds

Author(s): Dumeaux V; Massahi S; Bettauer V; Mottola A; Dukovny A; Khurdia SS; Costa ACBP; Omran RP; Simpson S; Xie JL; Whiteway M; Berman J; Hallett MT;

Candida albicans, an opportunistic human pathogen, poses a significant threat to human health and is associated with significant socio-economic burden. Current antifungal treatments fail, at least in part, because C. albicans can initiate a strong drug tolerance response that allows some cells to ...

Article GUID: 37888959


The neurophysiology of closed-loop auditory stimulation in sleep: A magnetoencephalography study

Author(s): Jourde HR; Merlo R; Brooks M; Rowe M; Coffey EBJ;

Closed-loop auditory stimulation (CLAS) is a brain modulation technique in which sounds are timed to enhance or disrupt endogenous neurophysiological events. CLAS of slow oscillation up-states in sleep is becoming a popular tool to study and enhance sleep's functions, as it increases slow oscillations, evokes sleep spindles and enhances memory consoli ...

Article GUID: 37675803


Inpatient Care Utilization Following Mobile Crisis Response Encounters Among Racial/Ethnic Minoritized Youth

Author(s): Lui JHL; Chen BC; Benson LA; Lin YR; Ruiz A; Lau AS;

Objective: There has been an increase in youth psychiatric emergencies and psychiatric inpatient hospitalizations in recent years. Mobile crisis responses (MCR) services offer an opportunity to meet acute youth mental health needs in the community and provide linkage to care. However, an understanding of MCR encounters as a care pathway is needed, includi ...

Article GUID: 37422107


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