Danger Changes the Way the Brain Consolidates Neutral Information; and Does So by Interacting with Processes Involved in the Encoding of That Information
 
				Authors: Omar A Qureshi
 
				
				
				
				Affiliations
				
					1 School of Psychology, University of New South Wales, Sydney, NSW, Australia. 
 
 
 
 
 2 Center for Studies in Behavioral Neurobiology, Department of Psychology, Concordia University, Montreal, QC, Canada. 
 
 
 
 
 3 School of Biomedical Sciences, Charles Sturt University, Orange, NSW, Australia. 
 
 
 
 
 4 School of Psychology, University of New South Wales, Sydney, NSW, Australia n.holmes@unsw.edu.au. 
				
				
				
				Description
					
					This study examined the effect of danger on consolidation of neutral information in two regions of the rat (male and female) medial temporal lobe: the perirhinal cortex (PRh) and basolateral amygdala complex (BLA). The neutral information was the association that forms between an auditory stimulus and a visual stimulus (labeled S2 and S1) across their pairings in sensory preconditioning. We show that, when the sensory preconditioning session is followed by a shocked context exposure, the danger...
				
 
				
					
					Keywords: NMDARs;  basolateral amygdala;  consolidation;  fear conditioning;  perirhinal cortex;  sensory preconditioning;  
 
				
				
				
				Links
				PubMed: https://pubmed.ncbi.nlm.nih.gov/36927572/
 
				
					DOI: 10.1523/JNEUROSCI.1796-22.2023