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An Anatomically Shaped Mitral Valve for Hemodynamic Testing

Author(s): Darwish A; Papolla C; Rieu R; Kadem L;

In vitro modeling of the left heart relies on accurately replicating the physiological conditions of the native heart. The targeted physiological conditions include the complex fluid dynamics coming along with the opening and closing of the aortic and mitral valves. As the mitral valve possess a highly sophisticated apparatus, thence, accurately modeling ...

Article GUID: 38228812


On Left Ventricle Stroke Work Efficiency in Children with Moderate Aortic Valve Regurgitation or Moderate Aortic Valve Stenosis

Author(s): Asaadi M; Mawad W; Djebbari A; Keshavardz-Motamed Z; Dahdah N; Kadem L;

The optimal timing for management of pediatric patients with moderate aortic valve disease [moderate aortic stenosis (modAS) or moderate aortic regurgitation (modAR)] remains unknown and largely unexplored. Although usually asymptomatic, the risk of increased left ventricular (LV) wall stress, irreversible myocardial fibrosis and sudden death in untreated ...

Article GUID: 34357415


Impact of Mitral Regurgitation on the Flow in a Model of a Left Ventricle.

Author(s): Papolla C, Darwish A, Kadem L, Rieu R

PURPOSE: Mitral regurgitation (MR) is the second most common valve disease in industrialized countries. Despite its high prevalence, little is known about its impact on the flow dynamics in the left ventricle (LV). Because of the interdependence between valvular function and hemodynamics in the heart chambers, an exploration of the dynamics in the LV coul ...

Article GUID: 33000444


Experimental Investigation of the Effect of Heart Rate On Flow in the Left Ventricle in Health and Disease -- Aortic Valve Regurgitation.

Author(s): Di Labbio G, Ben-Assa E, Kadem L

J Biomech Eng. 2019 Nov 01;: Authors: Di Labbio G, Ben-Assa E, Kadem L

Article GUID: 31701119


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