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Large language models deconstruct the clinical intuition behind diagnosing autism

Author(s): Stanley J; Rabot E; Reddy S; Belilovsky E; Mottron L; Bzdok D;

Efforts to use genome-wide assays or brain scans to diagnose autism have seen diminishing returns. Yet the clinical intuition of healthcare professionals, based on longstanding first-hand experience, remains the gold standard for diagnosis of autism. We leveraged deep learning to deconstruct and interrogate the logic of expert clinician intuition from cli ...

Article GUID: 40147442


Utilizing large language models for detecting hospital-acquired conditions: an empirical study on pulmonary embolism

Author(s): Cheligeer C; Southern DA; Yan J; Wu G; Pan J; Lee S; Martin EA; Jafarpour H; Eastwood CA; Zeng Y; Quan H;

Objectives: Adverse event detection from Electronic Medical Records (EMRs) is challenging due to the low incidence of the event, variability in clinical documentation, and the complexity of data formats. Pulmonary embolism as an adverse event (PEAE) is particularly difficult to identify using exi ...

Article GUID: 40105654


The effects of referential continuity on novel word learning in bilingual and monolingual preschoolers

Author(s): Moore C; Williams ME; Byers-Heinlein K;

Previous research suggests that monolingual children learn words more readily in contexts with referential continuity (i.e., repeated labeling of the same referent) than in contexts with referential discontinuity (i.e., referent switches). Here, we extended this work by testing monolingual and bilingual 3- and 4-year-olds' (N = 64) novel word learning ...

Article GUID: 39798202


Ion channel classification through machine learning and protein language model embeddings

Author(s): Ghazikhani H; Butler G;

Ion channels are critical membrane proteins that regulate ion flux across cellular membranes, influencing numerous biological functions. The resource-intensive nature of traditional wet lab experiments for ion channel identification has led to an increasing emphasis on computational techniques. This study extends our previous work on protein language mode ...

Article GUID: 39572876


Quebec-based parents' concerns regarding their children's multilingual development

Author(s): Quirk E; Brouillard M; Ahooja A; Ballinger S; Polka L; Byers-Heinlein K; Kircher R;

Many parents express concerns for their children's multilingual development, yet little is known about the nature and strength of these concerns - especially among parents in multilingual societies. This pre-registered, questionnaire-based study addresses this gap by examining the concerns of 821 Quebec-based parents raising infants and toddlers aged ...

Article GUID: 39055771


Cross-modal plasticity in children with cochlear implant: converging evidence from EEG and functional near-infrared spectroscopy

Author(s): Deroche MLD; Wolfe J; Neumann S; Manning J; Hanna L; Towler W; Wilson C; Bien AG; Miller S; Schafer E; Gemignani J; Alemi R; Muthuraman M; Koirala N; Gracco VL;

Over the first years of life, the brain undergoes substantial organization in response to environmental stimulation. In a silent world, it may promote vision by (i) recruiting resources from the auditory cortex and (ii) making the visual cortex more efficient. It is unclear when such changes occu ...

Article GUID: 38846536


Language Exposure and Brain Myelination in Early Development

Author(s): Fibla L; Forbes SH; McCarthy J; Mee K; Magnotta V; Deoni S; Cameron D; Spencer JP;

The language environment to which children are exposed has an impact on later language abilities as well as on brain development; however, it is unclear how early such impacts emerge. This study investigates the effects of children's early language environment and socioeconomic status (SES) on brain structure in infancy at 6 and 30 months of age (both ...

Article GUID: 37188518


Thinking aloud: effects on text comprehension by children with specific language impairment and their peers

Author(s): McClintock B; Pesco D; Martin-Chang S;

Background: Many lines of evidence now suggest that inferencing plays a substantial role in text comprehension. However, inferencing appears to be difficult for children with language impairments, many of whom are also struggling readers. Aims: To assess the effects of a 'think-aloud' procedure on inference generation and narrative text comprehen ...

Article GUID: 25180778


Exploiting protein language models for the precise classification of ion channels and ion transporters

Author(s): Ghazikhani H; Butler G;

This study introduces TooT-PLM-ionCT, a comprehensive framework that consolidates three distinct systems, each meticulously tailored for one of the following tasks: distinguishing ion channels (ICs) from membrane proteins (MPs), segregating ion transporters (ITs) from MPs, and differentiating ICs from ITs. Drawing upon the strengths of six Protein Languag ...

Article GUID: 38656743


ALBA: a model-driven framework for the automatic generation of android location-based apps

Author(s): Gharaat M; Sharbaf M; Zamani B; Hamou-Lhadj A;

In recent years, the number of smartphone users has increased dramatically. These users download millions of apps and use them for various services. Due to the significant demand for mobile apps, developers often seek faster development methods and more effective tools and techniques to generate these apps. Many of these apps are location-based apps in wh ...

Article GUID: 38624616


Transcoding of French numbers for first- and second-language learners in third grade

Author(s): Lafay A; Adrien E; Lonardo Burr SD; Douglas H; Provost-Larocque K; Xu C; LeFevre JA; Maloney EA; Osana HP; Skwarchuk SL; Wylie J;

Transcoding is the process of translating between spoken and written numbers, and it is correlated with other mathematical skills. In the present study, we investigated the link between French number writing of 49 students in the third grade (aged 7-9 years) and their language skills. Transcoding ...

Article GUID: 37129448


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