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Hypothalamic-pituitary-adrenal axis function in the offspring of parents with bipolar disorder and the impact of the family environment: A pilot study of the Reducing Unwanted Stress in the Home (RUSH) prevention program

Author(s): Ping EY; Herriot H; Iacono V; Serravalle L; Ellenbogen MA;

Background: The home environment of offspring of parents with bipolar disorder (OBD) has been characterized by high levels of stress and disorganization, which may impact development of the hypothalamic-pituitary-adrenal (HPA) axis and their subsequent risk for affective disorders. The present study examined the effects of a family-based preventative inte ...

Article GUID: 39357242


Hypothalamic-pituitary-adrenal axis functioning in offspring of parents with a major affective disorder: a meta-analytic review

Author(s): Serravalle L; Trespalacios F; Ellenbogen MA;

Because the offspring of parents with an affective disorder (OAD) are at high risk for developing mental disorders, and persons with an affective disorder (AD) show dysfunctional hypothalamic-pituitary-adrenal (HPA) axis activity, changes in HPA functioning in OAD might be an etiological risk factor that precedes the development of ADs. The primary aim of ...

Article GUID: 39207496


Indirect effects of HPA axis dysregulation in the association between peer victimization and depressed affect during early adolescence

Author(s): Adams RE; Santo JB; Bukowski WM;

Objective: Previous research has identified a link between peer victimization and depressive symptoms during adolescence. The goal of the current study is to examine the possible indirect effects of HPA axis dysregulation in the link between adolescent peer victimization and depressive symptoms. Method: A total of 113 boys (n = 61) and girls (n = 52) par ...

Article GUID: 34325208


Disaster-related prenatal maternal stress predicts HPA reactivity and psychopathology in adolescent offspring: Project Ice Storm.

Author(s): Yong Ping E, Laplante DP, Elgbeili G, Jones SL, Brunet A, King S

Psychoneuroendocrinology. 2020 Apr 21;117:104697 Authors: Yong Ping E, Laplante DP, Elgbeili G, Jones SL, Brunet A, King S

Article GUID: 32442863


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