Author(s): Feng Y; Lu H; Whiteway M; Jiang Y;

Fluconazole (FLC) tolerant phenotypes in Candida species contribute to persistent candidemia and the emergence of FLC resistance. Therefore, making FLC fungicidal and eliminating FLC tolerance are important for treating invasive fungal diseases (IFDs) caused by Candida species. However, the mechanisms of FLC tolerance in Candida species remain to be fully ...

Article GUID: 37918789

Author(s): Ge B; Najar F; Bouguila N;

In this paper, a weighted multivariate generalized Gaussian mixture model combined with stochastic optimization is proposed for point cloud registration. The mixture model parameters of the target scene and the scene to be registered are updated iteratively by the fixed point method under the framework of the EM algorithm, and the number of components is ...

Article GUID: 37754943

Author(s): Fortune D; Weisgarber B;

Belonging is a pervasive human need that is vital to our well-being as we age. Ageist attitudes, stereotyping, and life transitions tend to jeopardise older adults' experiences of belonging. Although community involvement can lead to the development of social relationships that support belonging in older adulthood, little is known about how belonging ...

Article GUID: 37518953

Author(s): Bloodgood EA; Bourns J; Lenczner M; Shibaike T; Tabet J; Melvin A; Wong WH;

We develop the concept of the nonprofit data environment as all data collected and reported in a country resulting from law implemented into practice. We map data environments across 20 countries and propose explanations for differences between the information nongovernmental organizations report (collected) and what is made publicly available (reported). ...

Article GUID: 36974198

Author(s): Khalili-Mahani N; Sawchuk K;

Background: Two fields of research and development targeting the needs of the aging population of the world are flourishing, successful aging and assistive information and communication technologies (A-ICTs). The risks of ageist stereotypes emerging from how we communicate in both discourses are long known. This raises questions about whether using specif ...

Article GUID: 36563033

Author(s): Pirhadi A; Salari S; Ahmad MO; Rivaz H; Xiao Y;

Purpose: In brain tumor surgery, tissue shift (called brain shift) can move the surgical target and invalidate the surgical plan. A cost-effective and flexible tool, intra-operative ultrasound (iUS) with robust image registration algorithms can effectively track brain shift to ensure surgical outcomes and safety. Methods: We proposed to employ a Siamese ...

Article GUID: 36306056

Author(s): Masoumi N; Rivaz H; Ahmad MO; Xiao Y;

Purpose: Diffeomorphic image registration is essential in many medical imaging applications. Several registration algorithms of such type have been proposed, but primarily for intra-contrast alignment. Currently, efficient inter-modal/contrast diffeomorphic registration, which is vital in numerous applications, remains a challenging task. Methods: We pro ...

Article GUID: 36173541

Author(s): Feng Q; An C; Chen Z; Owens E; Niu H; Wang Z;

Coastal environment is one of the most important ecological and socioeconomic areas. However, increasing energy demand and economic development lead to a continuous gas and oil exploration, production, and traffics, which notably raise the risk of oil spill accidents in coastal areas. Sensitivity assessment aiming to determine the coastal features that wo ...

Article GUID: 34271360

Author(s): Masoumi N; Belasso CJ; Ahmad MO; Benali H; Xiao Y; Rivaz H;

Purpose: Accurate multimodal registration of intraoperative ultrasound (US) and preoperative computed tomography (CT) is a challenging problem. Construction of public datasets of US and CT images can accelerate the development of such image registration techniques. This can help ensure the accuracy and safety of spinal surgeries using image-guided surgery ...

Article GUID: 33683544

Author(s): Lu H, Shrivastava M, Whiteway M, Jiang Y

Fluconazole has characteristics that make it widely used in the clinical treatment of C. albicans infections. However, fluconazole has only a fungistatic activity in C. albicans, therefore, in the long-term treatment of C. albicans infection with fluconazole, C. albicans has the potential to acquire fluconazole resistance. A promising approach to increase ...

Article GUID: 33587857

Author(s): Basotra N, Joshi S, Satyanarayana T, Pati PK, Tsang A, Chadha BS

Int J Biol Macromol. 2018 Mar;108:185-192 Authors: Basotra N, Joshi S, Satyanarayana T, Pati PK, Tsang A, Chadha BS

Article GUID: 29174359