Author(s): McKay MJ; Weber KA; Wesselink EO; Smith ZA; Abbott R; Anderson DB; Ashton-James CE; Atyeo J; Beach AJ; Burns J; Clarke S; Collins NJ; Coppieters MW; Cornwall J; Crawford RJ; De Martino E; Dunn AG; Eyles JP; Feng HJ; Fortin M; Franettovic ...

Disorders affecting the neurological and musculoskeletal systems represent international health priorities. A significant impediment to progress in trials of new therapies is the absence of responsive, objective, and valid outcome measures sensitive to early disease changes. A key finding in indi ...

Article GUID: 39590726

Author(s): Naghdi N; Elliott JM; Weber MH; Fehlings MG; Fortin M;

Study design: Cross-sectional study. Objectives: To examine the relationship between morphological changes of the deep extensor neck muscles in patients with degenerative cervical myelopathy (DCM) and the level of maximum spinal cord compression (MSCC) and canal compromise (MCC). A secondary objective was to examine the relationship between muscle morpho ...

Article GUID: 36289049

Author(s): Anstruther M; Sean M; Tétreault P; Fortin M;

Background and Objectives: Previous research has shown associations between atrophy and fatty infiltration of the lumbar paraspinal musculature and low back pain (LBP). However, few studies have examined longitudinal changes in healthy controls and individuals with LBP without intervention. We aimed to investigate the natural variations in lumbar paraspin ...

Article GUID: 38541216

Author(s): Ornowski J; Dziesinski L; Hess M; Krug R; Fortin M; Torres-Espin A; Majumdar S; Pedoia V; Bonnheim NB; Bailey JF;

Background: Paraspinal muscle fat infiltration is associated with spinal degeneration and low back pain, however, quantifying muscle fat using clinical magnetic resonance imaging (MRI) techniques continues to be a challenge. Advanced MRI techniques, including chemical-shift encoding (CSE) based w ...

Article GUID: 38222819

Author(s): Anstruther M; Rossini B; Zhang T; Liang T; Xiao Y; Fortin M;

Background: There is an increasing interest in assessing paraspinal morphology and composition in relation to low back pain (LBP). However, variations in methods and segmentation protocols contribute to the inconsistent findings in the literature. We present an on-line resource, the ParaspInaL muscLe segmentAtion pRoject (PILLAR, https://projectpillar.git ...

Article GUID: 37996857