Author(s): Kharma N; Bédard-Couture R;

Building on and extending existing definitions of robustness and evolvability, we propose and utilize new formal definitions, with matching measures, of robustness and evolvability of systems with genotypes and corresponding phenotypes. We explain and show how these measures are more general and more representative of the concepts they stand for, than the ...

Article GUID: 39098381

Author(s): Saad G; Greengross G;

No abstract available

Article GUID: 24999326

Author(s): Vongas JG; Al Hajj R;

Glass cliffs describe situations in which women are promoted to executive roles in declining organizations. To explain them, some authors suggest that people tend to "think crisis-think female." However, the root cause of this association remains elusive. Using several subfields of evolutionary theory, we argue that biology and culture have shaped the per ...

Article GUID: 26617564

Author(s): Kuzmin E; Baker TM; Lesluyes T; Monlong J; Abe KT; Coelho PP; Schwartz M; Del Corpo J; Zou D; Morin G; Pacis A; Yang Y; Martinez C; Barber J; Kuasne H; Li R; Bourgey M; Fortier AM; Davison PG; Omeroglu A; Guiot MC; Morris Q; Kleinman CL; ...

The basal breast cancer subtype is enriched for triple-negative breast cancer (TNBC) and displays consistent large chromosomal deletions. Here, we characterize evolution and maintenance of chromosome 4p (chr4p) loss in basal breast cancer. Analysis of The Cancer Genome Atlas data shows recurrent ...

Article GUID: 38517886

Author(s): Zhu Y; Cao H; Gao Z; Chen Z;

The identification of continuous pollution sources for rivers is of great concern for emergency response. Most studies focused on instantaneous river pollution sources and associated incidents. There is a dire need to address continuous pollution sources, as pollutant discharge may impose a major impact on the water ecosystem. Therefore, in this study, a ...

Article GUID: 38309421

Author(s): Chowdhury FR; Findlay BL;

Antibiotic resistance is a major threat to global health, claiming the lives of millions every year. With a nearly dry antibiotic development pipeline, novel strategies are urgently needed to combat resistant pathogens. One emerging strategy is the use of sequential antibiotic therapy, postulated to reduce the rate at which antibiotic resistance evolves. ...

Article GUID: 37726252

Author(s): Shaw AK; Lutscher F; Popovic L;

Our ability to understand population spread dynamics is complicated by rapid evolution, which renders simple ecological models insufficient. If dispersal ability evolves, more highly dispersive individuals may arrive at the population edge than less dispersive individuals (spatial sorting), accelerating spread. If individuals at the low-density population ...

Article GUID: 37198882

Author(s): Cosmo LG; Sales LP; Guimarães PR; Pires MM;

Linking local to regional ecological and evolutionary processes is key to understand the response of Earth's biodiversity to environmental changes. Here we integrate evolution and mutualistic coevolution in a model of metacommunity dynamics and use numerical simulations to understand how coevolution can shape species distribution and persistence in la ...

Article GUID: 36629106

Author(s): Zhu Y; Chen Z;

Source identification plays a vital role in implementing control measures for sudden river pollution incidents. In contrast to single-point source identification problems, there have been no investigations into inverse identification of multi-point emissions. In this study, an inverse model is developed based on the observed time series of pollutant conce ...

Article GUID: 36191500

Author(s): Schmidt C; Muñoz G; Lancaster LT; Lessard JP; Marske KA; Marshall KE; Garroway CJ;

Global biodiversity is organised into biogeographic regions that comprise distinct biotas. The contemporary factors maintaining differences in species composition between regions are poorly understood. Given evidence that populations with sufficient genetic variation can adapt to fill new habitats, it is surprising that more homogenisation of species asse ...

Article GUID: 35753949

Author(s): Tian X; Huang G; Song Z; An C; Chen Z;

Understanding the emission characteristics in the evolution of private vehicle fleet composition has become a key issue to be addressed to develop appropriate emission mitigation strategies in transportation sector. In this study, the influence of such evolution on on-road emissions was investigated based on a comprehensive dataset encompassing vehicle fl ...

Article GUID: 35709991