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Cell Fate Dynamics Reconstruction Identifies TPT1 and PTPRZ1 Feedback Loops as Master Regulators of Differentiation in Pediatric Glioblastoma-Immune Cell Networks

Author(s): Abicumaran Uthamacumaran

Pediatric glioblastoma is a complex dynamical disease that is difficult to treat due to its multiple adaptive behaviors driven largely by phenotypic plasticity. Integrated data science and network theory pipelines offer novel approaches to studying glioblas ...

Article GUID: 39420135


Prevalence of insomnia and use of sleep aids among adults in Canada

Author(s): Morin CM; Vézina-Im LA; Chen SJ; Ivers H; Carney CE; Chaput JP; Dang-Vu TT; Davidson JR; Belleville G; Lorrain D; Horn O; Robillard R; ...

Objectives: To estimate the prevalence of insomnia and the use of sleep aids among Canadian adults. Methods: Data were derived from a phone interview conducted (April to October 2023) with a strat ...

Article GUID: 39369578


Reduction of Cr(VI) by Bacillus toyonensis LBA36 and its effect on radish seedlings under Cr(VI) stress

Author(s): Tan A; Wang H; Zhang H; Zhang L; Yao H; Chen Z;

Chromium, being among the most toxic heavy metals, continues to demand immediate attention in the remediation of Cr-contaminated environments. In this study, a strain of LBA36 (Bacillus toyonensis) was isolated from heavy metal contaminated soil in Luanchua ...

Article GUID: 39346031


Adiposity and cardiac autonomic function in children with a family history of obesity

Author(s): Saade MB; Holden S; Kakinami L; McGrath JJ; Mathieu MÈ; Poirier P; Barnett TA; Beaucage P; Henderson M; ...

Purpose: Data on associations between adiposity and heart rate variability (HRV) in prepubertal children are limited. We examined the associations between adiposity indices and HRV, independent of ...

Article GUID: 39304555


Perceptions of carbon dioxide emission reductions and future warming among climate experts

Author(s): Wynes S; Davis SJ; Dickau M; Ly S; Maibach E; Rogelj J; Zickfeld K; Matthews HD;

The Intergovernmental Panel on Climate Change (IPCC) employs emission scenarios to explore a range of future climate outcomes but refrains from assigning probabilities to individual scenarios. However, IPCC authors have their own views on the likelihood of ...

Article GUID: 39280638


Emerging hazardous chemicals and biological pollutants in Canadian aquatic systems and remediation approaches: A comprehensive status report

Author(s): Adeola AO; Paramo L; Fuoco G; Naccache R;

Emerging contaminants can be natural or synthetic materials, as well as materials of a chemical, or biological origin; these materials are typically not controlled or monitored in the environment. Canada is home to nearly 7 % of the world's renewable wa ...

Article GUID: 39278485


Investigating the kinetics of marine and terrestrial organic carbon incorporation and degradation in coastal bulk sediment and water settings through isotopic lenses

Author(s): Mirzaei Y; Gélinas Y;

Coastal sediments are the main deposition center for allochthonous and autochthonous organic carbon (OC). The discharge of terrestrial biomass, anthropogenic activities, oceanic primary productivity, and natural events contribute to this carbon pool. The OC ...

Article GUID: 39117203


Cortical-subcortical interactions underlie processing of auditory predictions measured with 7T fMRI

Author(s): Ara A; Provias V; Sitek K; Coffey EBJ; Zatorre RJ;

Perception integrates both sensory inputs and internal models of the environment. In the auditory domain, predictions play a critical role because of the temporal nature of sounds. However, the precise contribution of cortical and subcortical structures in ...

Article GUID: 39087881


Expanding a Behavioral View on Digital Health Access: Drivers and Strategies to Promote Equity

Author(s): Kepper MM; Fowler LA; Kusters IS; Davis JW; Baqer M; Sagui-Henson S; Xiao Y; Tarfa A; Yi JC; Gibson B; Heron KE; Alberts NM; Burgermaster M; ...

The potential and threat of digital tools to achieve health equity has been highlighted for over a decade, but the success of achieving equitable access to health technologies remains challenging. ...

Article GUID: 39088246


Associations between valenced news and affect in daily life: Experimental and ecological momentary assessment approaches

Author(s): Shaikh SJ; McGowan AL; Lydon-Staley DM;

In 203 (mean age = 38.04 years, SD=12.05) participants, we tested the association between valenced news and affect using a 14-day, smartphone-based ecological momentary assessment protocol consisting of two components: 1) a once-per-day experimental protoco ...

Article GUID: 38919709


A randomized controlled trial of an acceptance-based, insight-inducing medication adherence therapy (AIM-AT) for adults with early-stage psychosis

Author(s): Chien WT; Chong YY; Bressington D; McMaster CW;

This study aimed to test the effectiveness of an acceptance-based medication adherence intervention for people with early-stage psychosis. An assessor-blind, three-arm randomized controlled trial design was used. One hundred and twenty-six participants who ...

Article GUID: 38908265


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