Author(s): Xiao Y; Gilmore G; Kai J; Lau JC; Peters T; Khan AR;

Population-averaged brain atlases, that are represented in a standard space with anatomical labels, are instrumental tools in neurosurgical planning and the study of neurodegenerative conditions. Traditional brain atlases are primarily derived from anatomical scans and contain limited information regarding the axonal organization of the white matter. With ...

Article GUID: 37663773

Author(s): Rousseau PN; Chakravarty MM; Steele CJ;

The cerebellum's involvement in cognitive, affective and motor functions is mediated by connections to different regions of the cerebral cortex. A distinctive feature of cortico-cerebellar loops that has been demonstrated in the animal work is a topographic organization that is preserved across its corticopontine, pontocerebellar, and cerebello-thalmo ...

Article GUID: 36252913

Author(s): Jossinger S; Sares A; Zislis A; Sury D; Gracco V; Ben-Shachar M;

Introduction: Individuals with persistent developmental stuttering display deficits in aligning motor actions to external cues (i.e., sensorimotor synchronization). Diffusion imaging studies point to stuttering-associated differences in dorsal, not ventral, white matter pathways, and in the cerebellar peduncles. Here, we studied microstructural white matt ...

Article GUID: 34856426

Author(s): Xiao Y; Peters TM; Khan AR;

Parkinson's disease (PD) is a progressive neurodegenerative disorder that is characterized by a range of motor and nonmotor symptoms, often with the motor dysfunction initiated unilaterally. Knowledge regarding disease-related alterations in white matter pathways can effectively help improve the understanding of the disease and propose targeted treatm ...

Article GUID: 34106502

Author(s): Kiar G, de Oliveira Castro P, Rioux P, Petit E, Brown ST, Evans AC, Glatard T

With an increase in awareness regarding a troubling lack of reproducibility in analytical software tools, the degree of validity in scientific derivatives and their downstream results has become unclear. The nature of reproducibility issues may vary across domains, tools, data sets, and computational infrastructures, but numerical instabilities are though ...

Article GUID: 32831546