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Data-driven methods distort optimal cutoffs and accuracy estimates of depression screening tools: a simulation study using individual participant data

Author(s): Bhandari PM; Levis B; Neupane D; Patten SB; Shrier I; Thombs BD; Benedetti A;

Objective: To evaluate, across multiple sample sizes, the degree that data-driven methods result in (1) optimal cutoffs different from population optimal cutoff and (2) bias in accuracy estimates. Study design and setting: A total of 1,000 samples of sample size 100, 200, 500 and 1,000 each were randomly drawn to simulate studies of different sample size ...

Article GUID: 33838273


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