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Navigating the nexus: climate dynamics and microplastics pollution in coastal ecosystems

Author(s): Ahmed Dar A; Chen Z; Sardar MF; An C;

Microplastics (MPs) pollution is an emerging environmental health concern, impacting soil, plants, animals, and humans through their entry into the food chain via bioaccumulation. Human activities such as improper solid waste dumping are significant sources that ultimately transport MPs into the water bodies of the coastal areas. Moreover, there is a comp ...

Article GUID: 38642636


A multiyear time series (2004-2012) of bacterial and archaeal community dynamics in a changing Arctic Ocean

Author(s): Kraemer SA; Ramachandran A; Onana VE; Li WKW; Walsh DA;

Climate change is profoundly impacting the Arctic, leading to a loss of multiyear sea ice and a warmer, fresher upper Arctic Ocean. The response of microbial communities to these climate-mediated changes is largely unknown. Here, we document the interannual variation in bacterial and archaeal communities across a 9-year time series of the Canada Basin tha ...

Article GUID: 38282643


New Megastigmane and Polyphenolic Components of Henna Leaves and Their Tumor-Specific Cytotoxicity on Human Oral Squamous Carcinoma Cell Lines

Author(s): Orabi MAA; Orabi EA; Awadh AAA; Alshahrani MM; Abdel-Wahab BA; Sakagami H; Hatano T;

Polyphenols have a variety of phenolic hydroxyl and carbonyl functionalities that enable them to scavenge many oxidants, thereby preserving the human redox balance and preventing a number of oxidative stress-related chronic degenerative diseases. In our ongoing investigation of polyphenol-rich plants in search of novel molecules, we resumed the investigat ...

Article GUID: 38001804


Overlooked Role of Bulk Nanobubbles in the Alteration and Motion of Microplastics in the Ocean Environment

Author(s): Wang Z; An C; Lee K; Feng Q;

The increasing enrichment of microplastics (MPs) in the shoreline environment poses both ecological and social-economic risks. The alteration and motion of MPs in the ocean under the effect of bulk nanobubbles (NBs) have been less extensively studied. In this study, we explored the behavior and movement of various MPs in the presence of bulk NBs. The role ...

Article GUID: 37477614


Species-specific protein-protein interactions govern the humanization of the 20S proteasome in yeast

Author(s): Sultana S; Abdullah M; Li J; Hochstrasser M; Kachroo AH;

Yeast and humans share thousands of genes despite a billion years of evolutionary divergence. While many human genes can functionally replace their yeast counterparts, nearly half of the tested shared genes cannot. For example, most yeast proteasome subunits are "humanizable", except subunits comprising the ß-ring core, including ß2c (HsPSMB7, a constitut ...

Article GUID: 37364278


Structural determination and anticholinesterase assay of C-glycosidic ellagitannins from Lawsonia inermis leaves: A study supported by DFT calculations and molecular docking

Author(s): Orabi MAA; Orabi EA; Abdel-Sattar ES; English AM; Hatano T; Elimam H;

An ellagitannin monomer, lythracin M (1), and a dimer, lythracin D (2), along with eight known monomers (3-10) were isolated from Lawsonia inermis (Lythraceae) leaves. Lythracin M (1) is a C-glycosidic ellagitannin with a flavogallonyl dilactone moiety that participates in the creation of a ?-lactone ring with the anomeric carbon of the glucose core. Lyth ...

Article GUID: 36423882


Sexual experience increases oxytocin, but not vasopressin, receptor densities in the medial preoptic area, ventromedial hypothalamus, and central amygdala of male rats

Author(s): Shann Ménard

Oxytocin (OT) and vasopressin (VP) are considered to be principal neurochemical substrates of bonding in monogamous species. We have reported previously that conditioning of a sexual partner preference in male rats resulted in conditioned activation of OT and VP neurons in hypothalamic paraventricular and supraoptc nuclei. Here we asked whether such condi ...

Article GUID: 36041295


Humanized yeast to model human biology, disease and evolution

Author(s): Kachroo AH; Vandeloo M; Greco BM; Abdullah M;

For decades, budding yeast, a single-cellular eukaryote, has provided remarkable insights into human biology. Yeast and humans share several thousand genes despite morphological and cellular differences and over a billion years of separate evolution. These genes encode critical cellular processes, the failure of which in humans results in disease. Althoug ...

Article GUID: 35661208


Polycyclic Aromatic Hydrocarbons in the Marine Atmosphere from the Western Pacific to the Southern Ocean: Spatial Variability, Gas/Particle Partitioning, and Source Apportionment

Author(s): Zhang X; Zhang ZF; Zhang X; Zhu FJ; Li YF; Cai M; Kallenborn R;

The spatial variability of polycyclic aromatic hydrocarbons (PAHs) in the marine atmosphere contributes to the understanding of the global sources, fate, and impact of this contaminant. Few studies conducted to measure PAHs in the oceanic atmosphere have covered a large scale, especially in the Southern Ocean. In this study, high-volume air samples were t ...

Article GUID: 35476391


Pesticides in the atmosphere and seawater in a transect study from the Western Pacific to the Southern Ocean: The importance of continental discharges and air-seawater exchange

Author(s): Zhang X; Zhang X; Zhang ZF; Yang PF; Li YF; Cai M; Kallenborn R;

The global oceans are known as terminal sink or secondary source for diffusive emission of organochlorine pesticides (OCPs) and selected current used pesticides (CUPs) into the overlaying atmosphere. Many pesticides have been widely produced worldwide, subsequently applied, and released into the environment. However, information on the occurrence patterns ...

Article GUID: 35452973


BioMiCo: a supervised Bayesian model for inference of microbial community structure.

Author(s): Shafiei M, Dunn KA, Boon E, MacDonald SM, Walsh DA, Gu H, Bielawski JP

Microbiome. 2015;3:8 Authors: Shafiei M, Dunn KA, Boon E, MacDonald SM, Walsh DA, Gu H, Bielawski JP

Article GUID: 25774293


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