Author(s): Singh D; Memari E; He S; Yusefi H; Helfield B;
Over the past two decades, there has been tremendous and exciting progress toward extending the use of medical ultrasound beyond a traditional imaging tool. Ultrasound contrast agents, typically used for improved visualization of blood flow, have been explo ...
Article GUID: 38983873
Author(s): Memari E; Khan D; Alkins R; Helfield B;
Focused ultrasound (FUS) combined with intravascularly circulating microbubbles can transiently increase the permeability of the blood-brain barrier (BBB) to enable targeted therapeutic delivery to the brain, the clinical testing of which is currently under ...
Article GUID: 38266715
Author(s): Yusefi H; Helfield B;
Phospholipid encapsulated ultrasound contrast agents have proven to be a powerful addition in diagnostic imaging and show emerging applications in targeted therapy due to their resonant and nonlinear scattering. Microbubble response is affected by their int ...
Article GUID: 38217906
Author(s): Memari E; Hui F; Yusefi H; Helfield B;
The local fluid dynamics experienced by circulating microbubbles vary across different anatomical sites, which can influence ultrasound-mediated therapeutic delivery efficacy. This study aimed to elucidate the effect of fluid flow rate in combination with r ...
Article GUID: 37150403
Author(s): He S; Singh D; Yusefi H; Helfield B;
In endothelial cells, microRNA-126 (miR-126) promotes angiogenesis, and modulating the intracellular levels of this gene could suggest a method to treat cardiovascular diseases such as ischemia. Novel ultrasound-stimulated microbubbles offer a means to deli ...
Article GUID: 36559150
Author(s): Yusefi H; Helfield B;
Ultrasound-driven microbubbles, typically between 1 and 8 µm in diameter, are resonant scatterers that are employed as diagnostic contrast agents and emerging as potentiators of targeted therapies. Microbubbles are administered in populations whereby their ...
Article GUID: 36223708
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