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A protocol for trustworthy EEG decoding with neural networks

Author(s): Borra D; Magosso E; Ravanelli M;

Deep learning solutions have rapidly emerged for EEG decoding, achieving state-of-the-art performance on a variety of decoding tasks. Despite their high performance, existing solutions do not fully address the challenge posed by the introduction of many hyperparameters, defining data pre-processing, network architecture, network training, and data augment ...

Article GUID: 39549492


Comprehensive Analysis of Age- and Sex-Related Expression of the Chaperone Protein Sigma-1R in the Mouse Brain

Author(s): Tarmoun K; Lachance V; Le Corvec V; Bélanger SM; Beaucaire G; Kourrich S;

Sigma-1R (S1R) is a ubiquitously distributed protein highly expressed in the brain and liver. It acts as a ligand-inducible chaperone protein localized at the endoplasmic reticulum. S1R participates in several signaling pathways that oversee diverse cellular and neurological functions, such as calcium and proteome homeostasis, neuronal activity, memory, a ...

Article GUID: 39335377


Impact of Stimulation Frequency on Verbal Fluency Following Bilateral Subthalamic Nucleus Deep Brain Stimulation in Parkinson's Disease

Author(s): Busteed L; García-Sánchez C; Pascual-Sedano B; Grunden N; Gironell A; Kulisevsky J; Pagonabarraga J;

Objective: The effects of stimulation frequency on verbal fluency (VF) following subthalamic nucleus deep brain stimulation (STN-DBS) in Parkinson's disease (PD) are not well understood. The present study examines the impact stimulation frequency has on VF following bilateral STN-DBS in PD. ...

Article GUID: 39127889


Feasibility and acceptability of an adapted peer-based walking intervention for adults with moderate-to-severe traumatic brain injury

Author(s): Quilico EL; Wilkinson S; Duncan LR; Sweet SN; Alarie C; Bédard E; Gheta I; Brodeur CL; Colantonio A; Swaine BR;

Purpose: To examine the feasibility and acceptability of a 6-week peer-based walking intervention for adults with moderate-to-severe TBI with telehealth supports. Materials and methods: Pre-post feasibility trial with 18 community-dwelling adults (10 men; 8 women) with moderate-to-severe TBI age ...

Article GUID: 39051571


Open access segmentations of intraoperative brain tumor ultrasound images

Author(s): Behboodi B; Carton FX; Chabanas M; de Ribaupierre S; Solheim O; Munkvold BKR; Rivaz H; Xiao Y; Reinertsen I;

Purpose: Registration and segmentation of magnetic resonance (MR) and ultrasound (US) images could play an essential role in surgical planning and resectioning brain tumors. However, validating these techniques is challenging due to the scarcity of publicly accessible sources with high-quality gr ...

Article GUID: 39047165


The BDNF Val66Met polymorphism and health-related quality of life in youth with obesity

Author(s): Goldfield GS; Cameron JD; Sigal RJ; Kenny GP; Prud' homme D; Ngu M; Alberga AS; Doucette S; Goldfield DB; Tulloch H; Thai H; Simas KR; Walsh J;

The brain derived-neurotrophic factor (BDNF) Val66Met polymorphism causes functional changes in BDNF, and is associated with obesity and some psychiatric disorders, but its relationship to health-related quality of life (HRQoL) remains unknown. This study examined, in youth with obesity, whether ...

Article GUID: 38997217


EEG/MEG source imaging of deep brain activity within the maximum entropy on the mean framework: Simulations and validation in epilepsy

Author(s): Afnan J; Cai Z; Lina JM; Abdallah C; Delaire E; Avigdor T; Ros V; Hedrich T; von Ellenrieder N; Kobayashi E; Frauscher B; Gotman J; Grova C;

Electro/Magneto-EncephaloGraphy (EEG/MEG) source imaging (EMSI) of epileptic activity from deep generators is often challenging due to the higher sensitivity of EEG/MEG to superficial regions and to the spatial configuration of subcortical structures. We previously demonstrated the ability of the ...

Article GUID: 38994740


Cross-modal plasticity in children with cochlear implant: converging evidence from EEG and functional near-infrared spectroscopy

Author(s): Deroche MLD; Wolfe J; Neumann S; Manning J; Hanna L; Towler W; Wilson C; Bien AG; Miller S; Schafer E; Gemignani J; Alemi R; Muthuraman M; Koirala N; Gracco VL;

Over the first years of life, the brain undergoes substantial organization in response to environmental stimulation. In a silent world, it may promote vision by (i) recruiting resources from the auditory cortex and (ii) making the visual cortex more efficient. It is unclear when such changes occu ...

Article GUID: 38846536


Language Exposure and Brain Myelination in Early Development

Author(s): Fibla L; Forbes SH; McCarthy J; Mee K; Magnotta V; Deoni S; Cameron D; Spencer JP;

The language environment to which children are exposed has an impact on later language abilities as well as on brain development; however, it is unclear how early such impacts emerge. This study investigates the effects of children's early language environment and socioeconomic status (SES) on brain structure in infancy at 6 and 30 months of age (both ...

Article GUID: 37188518


Computational neuroscience across the lifespan: Promises and pitfalls

Author(s): van den Bos W; Bruckner R; Nassar MR; Mata R; Eppinger B;

In recent years, the application of computational modeling in studies on age-related changes in decision making and learning has gained in popularity. One advantage of computational models is that they provide access to latent variables that cannot be directly observed from behavior. In combination with experimental manipulations, these latent variables c ...

Article GUID: 29066078


Athlete Fear Avoidance, Depression, and Anxiety Are Associated with Acute Concussion Symptoms in Athletes

Author(s): Patlan I; Gamelin G; Khalaj K; Castonguay T; Dover G;

ackground: Assessing sport-related concussions in athletes presents challenges due to symptom variability. This study aimed to explore the relationship between acute concussion symptoms and athlete fear avoidance, pain catastrophizing, depression, and anxiety. Anxiety and depression have previously been associated with the number of symptoms after a concu ...

Article GUID: 38673675


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