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Geospatial analysis reveals a hotspot of fecal bacteria in Canadian prairie lakes linked to agricultural non-point sources

Author(s): Oliva A; Onana VE; Garner RE; Kraemer SA; Fradette M; Walsh DA; Huot Y;

Lakes are sentinels of environmental changes within their watersheds including those induced by a changing climate and anthropogenic activities. In particular, contamination originating from point or non-point sources (NPS) within watersheds might be reflected in changes in the bacterial composition of lake water. We assessed the abundance of potentially ...

Article GUID: 36653256


Gut colonization by Proteobacteria alters host metabolism and modulates cocaine neurobehavioral responses

Author(s): Cuesta S; Burdisso P; Segev A; Kourrich S; Sperandio V;

Gut-microbiota membership is associated with diverse neuropsychological outcomes, including substance use disorders (SUDs). Here, we use mice colonized with Citrobacter rodentium or the human ?-Proteobacteria commensal Escherichia coli HS as a model to examine the mechanistic interactions between gut microbes and host responses to cocaine. We find that co ...

Article GUID: 36323315


Dual acting acid-cleavable self-assembling prodrug from hyaluronic acid and ciprofloxacin: A potential system for simultaneously targeting bacterial infections and cancer

Author(s): Ibrahim UH; Devnarain N; Mohammed M; Omolo CA; Gafar MA; Salih M; Pant A; Shunmugam L; Mocktar C; Khan R; Oh JK; Govender T;

The incidence and of bacterial infections, and resulting mortality, among cancer patients is growing dramatically, worldwide. Several therapeutics have been reported to have dual anticancer and antibacterial activity. However, there is still an urgent need to develop new drug delivery strategies ...

Article GUID: 36150574


Evidence of an intracellular interaction between the Escherichia coli enzymes EntC and EntB and identification of a potential electrostatic channeling surface

Author(s): Ouellette S; Pakarian P; Bin X; Pawelek PD;

Siderophores are high-affinity small-molecule chelators employed by bacteria to acquire iron from the extracellular environment. The Gram-negative bacterium Escherichia coli synthesizes and secretes enterobactin, a tris-catechol siderophore. Enterobactin is synthesized by six cytoplasmic enzyme activities: EntC, EntB (isochorismatase (IC) domain), EntA, E ...

Article GUID: 35952947


Comparing microscopy and DNA metabarcoding techniques for identifying cyanobacteria assemblages across hundreds of lakes

Author(s): MacKeigan PW; Garner RE; Monchamp MÈ; Walsh DA; Onana VE; Kraemer SA; Pick FR; Beisner BE; Agbeti MD; da Costa NB; Shapiro BJ; Gregory-Eaves I;

Accurately identifying the species present in an ecosystem is vital to lake managers and successful bioassessment programs. This is particularly important when monitoring cyanobacteria, as numerous taxa produce toxins and can have major negative impacts on aquatic ecosystems. Increasingly, DNA-ba ...

Article GUID: 35287928


Treatment of decentralized low-Strength livestock wastewater using microcurrent-assisted multi-soil-layering systems: Performance Assessment and microbial analysis

Author(s): Liu C; Huang G; Song P; An C; Zhang P; Shen J; Ren S; Zhao K; Huang W; Xu Y; Zheng R;

Discharge of decentralized livestock wastewater without effective treatment has become a common problem in rural areas, threatening the regional water environment. A new microcurrent-assisted multi-soil-layering (MSL) system was developed for treating rural decentralized livestock wastewater. The results showed the highest removal rates of chemical oxygen ...

Article GUID: 34999101


Detection of Fusobacterium nucleatum subspecies in the saliva of pre-colorectal cancer patients, using tandem mass spectrometry

Author(s): Morsi H; Golizeh M; Brosseau N; Janati AI; Emami E; Ndao M; Tran SD;

Objective: Rising evidence links Fusobacterium nucleatum (F. nucleatum) with its four subspecies; nucleatum, polymorphum, animalis, and vincentii, with the development of colorectal cancer (CRC) and its precursor colorectal adenoma (CRA). This study aims to optimize a technique for and explore the capability of matrix-assisted laser-desorption ionization- ...

Article GUID: 34929558


Bound detergent molecules in bacterial reaction centers facilitate detection of tetryl explosive.

Author(s): Modafferi D, Zazubovich V, Kálmán L

Photosynth Res. 2020 Jul 06;: Authors: Modafferi D, Zazubovich V, Kálmán L

Article GUID: 32632533


Modelling Free-Living and Particle-Associated Bacterial Assemblages across the Deep and Hypoxic Lower St. Lawrence Estuary.

Author(s): Cui TT, Dawson TJ, McLatchie S, Dunn K, Bielawski J, Walsh DA

mSphere. 2020 May 20;5(3): Authors: Cui TT, Dawson TJ, McLatchie S, Dunn K, Bielawski J, Walsh DA

Article GUID: 32434843


Exploring the use of ceramic disk filter coated with Ag/ZnO nanocomposites as an innovative approach for removing Escherichia coli from household drinking water.

Author(s): Huang J, Huang G, An C, Xin X, Chen X, Zhao Y, Feng R, Xiong W

Chemosphere. 2019 Dec 06;245:125545 Authors: Huang J, Huang G, An C, Xin X, Chen X, Zhao Y, Feng R, Xiong W

Article GUID: 31864067


Using the endogenous CRISPR-Cas system of Heliobacterium modesticaldum to delete the photochemical reaction center core subunit gene.

Author(s): Baker PL, Orf GS, Kevershan K, Pyne ME, Bicer T, Redding KE

Appl Environ Microbiol. 2019 Sep 20;: Authors: Baker PL, Orf GS, Kevershan K, Pyne ME, Bicer T, Redding KE

Article GUID: 31540988


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