Author(s): Yusefi H; Helfield B;

Clinical ultrasound contrast agent microbubbles remain intravascular and are between 1-8 µm in diameter, with a volume-weighted mean size of 2-3 µm. Despite their worldwide clinical utility as a diagnostic contrast agent, and their continued and ongoing success as a local therapeutic vector, the fundamental interplay between microbubbles - including bubbl ...

Article GUID: 39705920

Author(s): Patrick Viet-Quoc N; Thien Thanh DV; Philippe L; Sebastien C; Lidia S; Philippe D;

Objective: This systematic review and meta-analysis evaluates the efficacy in improving sleep quality and safety of hypnotics in individuals aged 65 years or older compared to those under 65 years. Methods: MEDLINE, EMBASE, Web of Science, and EBM Reviews were searched for randomized clinical trials comparing hypnotics to the placebo in adults with chron ...

Article GUID: 39603114

Author(s): Ghazikhani H; Butler G;

Ion channels are critical membrane proteins that regulate ion flux across cellular membranes, influencing numerous biological functions. The resource-intensive nature of traditional wet lab experiments for ion channel identification has led to an increasing emphasis on computational techniques. This study extends our previous work on protein language mode ...

Article GUID: 39572876

Author(s): Mohanathas N; Montanari L; Gabriel GA; Downey R; Li KZH; Campos JL;

Age-related hearing loss is a risk factor for mobility problems and falls, possibly due to poor access to spatial sounds or the higher allocation of attention required to listen, thereby reducing cognitive resources to support mobility. Introducing stabilizing spatial sounds or reducing cognitive load through hearing aids could possibly improve balance pe ...

Article GUID: 39567644

Author(s): Beemelmanns A; Bouchard R; Michaelides S; Normandeau E; Jeon HB; Chamlian B; Babin C; Hénault P; Perrot O; Harris LN; Zhu X; Fraser D; Bernatchez L; Moore JS;

Single nucleotide polymorphism (SNP) panels are powerful tools for assessing the genetic population structure and dispersal of fishes and can enhance management practices for commercial, recreational and subsistence mixed-stock fisheries. Arctic Char (Salvelinus alpinus), Brook Trout (Salvelinus ...

Article GUID: 39552382

Author(s): Yalman A; Jafari A; Léger É; Mastroianni MA; Teimouri K; Savoji H; Collins DL; Kadem L; Xiao Y;

Background: Physical vascular phantoms are instrumental in studying intracranial aneurysms and testing relevant imaging tools and training systems to provide improved clinical care. Current vascular phantom production methods have major limitations in capturing the biophysical and morphological c ...

Article GUID: 39546636

Author(s): Fu J; Guo T; Li H; Liu W; Chen Z; Wang X; Guo J;

In this study, a functionally stable insoluble Cu/Fe nanoparticles (Cu/Fe NPs) were synthesized and applied denitrification with different contaminants. The results showed that 50 mg/L Cu/Fe NPs increased NO3--N reduction rate up to 14.3 mg/(L·h) about 3 folds compared with the control system (4.7 mg/(L·h)), and Cu/Fe NPs exhibited excellent restorative e ...

Article GUID: 39542060

Author(s): Abtahi M; Athienitis A; Delcroix B;

This paper presents a methodology to develop archetype gray-box models and use them in an economic model-based predictive control algorithm to simulate optimal heating load management in response to a newly-introduced static time-of-use tariff for Québec's residential sector, rate Flex-D. The methodology is evaluated through a case study, wherein in s ...

Article GUID: 39507415

Author(s): Swami V; Maïano C; Morin AJS;

Traditionally, assessments of factor validity of body image instruments have relied on exploratory or confirmatory factor analysis. However, the emergence of exploratory structural equation modeling (ESEM), a resurgence of interest in bifactor models, and the ability to combine both models (bifactor-ESEM) is beginning to shape the future of body image res ...

Article GUID: 39492241

Author(s): Morin CM; Khullar A; Robillard R; Desautels A; Mak MSB; Dang-Vu TT; Chow W; Habert J; Lessard S; Alima L; Ayas NT; MacFarlane J; Kendzerska T; Lee EK; Carney CE;

Objective: The lack of current Canadian practice guidelines for the management of insomnia poses a challenge for healthcare providers (HCP) in selecting the appropriate treatment options. This study aimed to establish expert consensus recommendations for the management of chronic insomnia in Cana ...

Article GUID: 39481275

Author(s): Yuan TY; Bouzari N; Bains A; Cohen TR; Kakinami L;

Objective: Weight-control compensatory behaviors appear to be a commonly utilized strategy for health management. Individuals engaging in such behaviors believe that the negative consequences from unhealthy behaviors will be neutralized by the positive consequences of healthy behaviors. Existing research has not reached a consensus on whether such behavio ...

Article GUID: 39469249