Author(s): Jones Z; Drouin S; Kersten-Oertel M;

Purpose: Virtual reality (VR) can offer immersive platforms for segmenting complex medical images to facilitate a better understanding of anatomical structures for training, diagnosis, surgical planning, and treatment evaluation. These applications rely on user interaction within the VR environment to manipulate and interpret medical data. However, the op ...

Article GUID: 40402355

Author(s): Bin X; Pawelek PD;

The Escherichia coli enterobactin biosynthetic protein EntB is a bifunctional enzyme that catalyzes hydrolysis of isochorismate via its N-terminal isochorismatase (IC) domain, and then transfers phosphopantetheinylated 2,3-DHB to EntF via the EntB C-terminal aryl carrier protein (ArCP) domain. Here we used a fluorescence anisotropy binding assay to invest ...

Article GUID: 40400396

Author(s): Avigdor T; Peter-Derex L; Ho A; Schiller K; Wang Y; Abdallah C; Delaire E; Jaber K; Travnicek V; Grova C; Frauscher B;

Although rapid eye movement (REM) sleep is often thought of as a singular state, it consists of two substates, phasic and tonic REM, defined by the presence (respectively absence) of bursts of rapid eye movements. These two substates have distinct EEG signatures and functional properties. However ...

Article GUID: 40394955

Author(s): Schebb NH; Kampschulte N; Hagn G; Plitzko K; Meckelmann SW; Ghosh S; Joshi R; Kuligowski J; Vuckovic D; Botana MT; Sánchez-Illana Á; Zandkarimi F; Das A; Yang J; Schmidt L; Checa A; Roche HM; Armando AM; Edin ML; Lih FB; Aristizabal-Hena ...

Several oxylipins are potent lipid mediators that regulate diverse aspects of health and disease and whose quantitative analysis by liquid chromatography-mass spectrometry (LC-MS) presents substantial technical challenges. As members of the lipidomics community, we developed technical recommendat ...

Article GUID: 40392938

Author(s): Gumuchian ST; Boyle A; Kennedy G; Wong SF; Ellenbogen MA;

Despite high recurrence rates in major depressive disorder (MDD), little is known about the factors influencing recurrence. Understanding the changes that occur between major depressive episodes (MDEs) is imperative. It is possible that being fearful of experiencing another MDE may lead to cognitive and behavioural changes that increase MDD recurrence ris ...

Article GUID: 40391691

Author(s): Little SR; Rahbari N; Hajiaghayi M; Gholizadeh F; Cloarec-Ung FM; Phillips J; Sinha H; Hirukawa A; Knapp DJHF; Darlington PJ; Shih SCC;

Genetically engineering human immune cells has been shown to be an effective approach for developing novel cellular therapies to treat a wide range of diseases. To expand the scope of these cellular therapies while solving persistent challenges, extensive research and development is still require ...

Article GUID: 40390294

Author(s): Comeau P; Leite ML; Manso A;

The main objective of this study was to develop a natural curcumin-loaded varnish that responds to blue light in an antimicrobial photodynamic therapy-based approach with photoelimination of targeted cells. Fluoride-free curcumin-loaded varnish (CUR-V) consisting of gum rosin (80 wt%) and ethanol (20 wt%) was loaded with 0, 0.25, and 10.0 wt% curcumin and ...

Article GUID: 40387395

Author(s): Zajac Z; Helfield B; Williams R; Sheeran P; Tremblay-Darveau C; Yoo K; Burns PN;

Objectives: The development of low boiling point liquid droplets as phase-change contrast agents allows for the local creation of microbubbles at a point of interest in vivo. Although there are many possible applications, few investigations have used selectively created microbubble boluses to measure volumetric flowrate. In this study, the flow ratio betw ...

Article GUID: 40387284

Author(s): Wang X; Du Z; Song Z; Liu M; He P; Feng L; Chen Z; Chen Q;

This study investigated the oil pollution remediation ability of konjac glucomannan (KGM) aerogel immobilized Chlorella vulgaris LH-1 (C. vulgaris). The KGM aerogel exhibited a high porosity of 86.83 %, and with the change of crude oil concentration (1-10 g/L), the crude oil adsorption efficiency of KGM aerogel was up to 18.75 %. The KGM aerogel carrier e ...

Article GUID: 40381443

Author(s): Forouhar V; Edache IY; Alberga AS;

The majority of Canadian adults are not meeting the recommended physical activity and sedentary behaviour guidelines. Previous studies have highlighted experiences of weight bias as a potential barrier to physical activity and an enabler of sedentary behaviours. Few studies have examined whether endorsing or internalizing weight bias is associated with th ...

Article GUID: 40374859

Author(s): Delaire É; Vincent T; Cai Z; Machado A; Hugueville L; Schwartz D; Tadel F; Cassani R; Bherer L; Lina JM; Pélégrini-Issac M; Grova C;

Significance: Understanding the brain's complex functions requires multimodal approaches that combine data from various neuroimaging techniques. Functional near-infrared spectroscopy (fNIRS) offers valuable insights into hemodynamic responses, complementing other modalities such as electroenc ...

Article GUID: 40375973

Author(s): Pinto SM; Cheung JPY; Samartzis D; Karppinen J; Zheng YP; Pang MYC; Fortin M; Wong AYL;

Background: Although individuals with chronic low back pain (CLBP) show increased fatty infiltration in the lumbar multifidus muscle (LMM), it remains unclear whether LMM changes are related to clinical outcomes (such as pain and disability) after considering confounders (spinal phenotypes, fear-avoidance beliefs [FABs] and insomnia). This study examined: ...

Article GUID: 40376565