Author(s): Mignacca M; Brugiapaglia S; Bramburger JJ;
Dynamic mode decomposition (DMD) is a numerical method that seeks to fit time-series data to a linear dynamical system. In doing so, DMD decomposes dynamic data into spatially coherent modes that evolve in time according to exponential growth/decay or with a fixed frequency of oscillation. A widespread application of DMD has been to video, where one inter ...
Article GUID: 40421310
Author(s): Raheja Y; Singh V; Gaur VK; Tsang A; Chadha BS;
In this study, two thermostable endoglucanases (Rem_GH5EG and Rem_GH7EG) from Rasamsonia emersonii were heterologously expressed in Pichia pastoris and characterized to evaluate their potential for industrial biomass saccharification. Rem_GH5EG demonstrated markedly superior catalytic efficiency toward barley ß-glucan (kcat/Km = 6.3 × 10-3/mg mL/min), whi ...
Article GUID: 40418313
Author(s): Gagné N; Greenlaw KM; Coffey EBJ;
Hearing-in-noise (HIN) is a challenging task that is essential to human functioning in social, vocational, and educational contexts. Successful speech perception in noisy settings is thought to rely in part on the brain's ability to enhance neural representations of attended speech. In everyday HIN situations, important features of speech (i.e., pitch ...
Article GUID: 40412301
Author(s): Gholizadeh F; Hajiaghayi M; Choi JS; Little SR; Rahbari N; Kargar M; Brotto K; Han E; Shih SCC; Darlington PJ;
Memory T helper (Th) cells, generated in response to immunogenic challenges, are crucial in orchestrating adaptive immune responses. Acetylcholine (ACh), a key neurotransmitter of the parasympathetic nervous system, modulates immune function via muscarinic ACh receptors (mAChRs). This study inves ...
Article GUID: 40405417
Author(s): Jones Z; Drouin S; Kersten-Oertel M;
Purpose: Virtual reality (VR) can offer immersive platforms for segmenting complex medical images to facilitate a better understanding of anatomical structures for training, diagnosis, surgical planning, and treatment evaluation. These applications rely on user interaction within the VR environment to manipulate and interpret medical data. However, the op ...
Article GUID: 40402355
Author(s): Bin X; Pawelek PD;
The Escherichia coli enterobactin biosynthetic protein EntB is a bifunctional enzyme that catalyzes hydrolysis of isochorismate via its N-terminal isochorismatase (IC) domain, and then transfers phosphopantetheinylated 2,3-DHB to EntF via the EntB C-terminal aryl carrier protein (ArCP) domain. Here we used a fluorescence anisotropy binding assay to invest ...
Article GUID: 40400396
Author(s): Avigdor T; Peter-Derex L; Ho A; Schiller K; Wang Y; Abdallah C; Delaire E; Jaber K; Travnicek V; Grova C; Frauscher B;
Although rapid eye movement (REM) sleep is often thought of as a singular state, it consists of two substates, phasic and tonic REM, defined by the presence (respectively absence) of bursts of rapid eye movements. These two substates have distinct EEG signatures and functional properties. However ...
Article GUID: 40394955
Author(s): Schebb NH; Kampschulte N; Hagn G; Plitzko K; Meckelmann SW; Ghosh S; Joshi R; Kuligowski J; Vuckovic D; Botana MT; Sánchez-Illana Á; Zandkarimi F; Das A; Yang J; Schmidt L; Checa A; Roche HM; Armando AM; Edin ML; Lih FB; Aristizabal-Hena ...
Several oxylipins are potent lipid mediators that regulate diverse aspects of health and disease and whose quantitative analysis by liquid chromatography-mass spectrometry (LC-MS) presents substantial technical challenges. As members of the lipidomics community, we developed technical recommendat ...
Article GUID: 40392938
Author(s): Gumuchian ST; Boyle A; Kennedy G; Wong SF; Ellenbogen MA;
Despite high recurrence rates in major depressive disorder (MDD), little is known about the factors influencing recurrence. Understanding the changes that occur between major depressive episodes (MDEs) is imperative. It is possible that being fearful of experiencing another MDE may lead to cognitive and behavioural changes that increase MDD recurrence ris ...
Article GUID: 40391691
Author(s): Little SR; Rahbari N; Hajiaghayi M; Gholizadeh F; Cloarec-Ung FM; Phillips J; Sinha H; Hirukawa A; Knapp DJHF; Darlington PJ; Shih SCC;
Genetically engineering human immune cells has been shown to be an effective approach for developing novel cellular therapies to treat a wide range of diseases. To expand the scope of these cellular therapies while solving persistent challenges, extensive research and development is still require ...
Article GUID: 40390294
Author(s): Comeau P; Leite ML; Manso A;
The main objective of this study was to develop a natural curcumin-loaded varnish that responds to blue light in an antimicrobial photodynamic therapy-based approach with photoelimination of targeted cells. Fluoride-free curcumin-loaded varnish (CUR-V) consisting of gum rosin (80 wt%) and ethanol (20 wt%) was loaded with 0, 0.25, and 10.0 wt% curcumin and ...
Article GUID: 40387395
Author(s): Zajac Z; Helfield B; Williams R; Sheeran P; Tremblay-Darveau C; Yoo K; Burns PN;
Objectives: The development of low boiling point liquid droplets as phase-change contrast agents allows for the local creation of microbubbles at a point of interest in vivo. Although there are many possible applications, few investigations have used selectively created microbubble boluses to measure volumetric flowrate. In this study, the flow ratio betw ...
Article GUID: 40387284
