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Genetic, Structural, and Functional Evidence Link TMEM175 to Synucleinopathies

Author(s): Krohn L; Öztürk TN; Vanderperre B; Ouled Amar Bencheikh B; Ruskey JA; Laurent SB; Spiegelman D; Postuma RB; Arnulf I; Hu MTM; Dauvilliers Y; Högl B; Stefani A; Monaca CC; Plazzi G; Antelmi E; Ferini-Strambi L; Heidbreder A; Rudakou U; Co ...

Objective: The TMEM175/GAK/DGKQ locus is the 3rd strongest risk locus in genome-wide association studies of Parkinson disease (PD). We aimed to identify the specific disease-associated variants in this locus, and their potential implications. Methods: Full sequencing of TMEM175/GAK/DGKQ followed ...

Article GUID: 31658403


Worsening Perceptions of Family Connectedness and Parent Support for Lesbian, Gay, and Bisexual Adolescents.

Author(s): Watson RJ, Rose HA, Doull M, Adjei J, Saewyc E

J Child Fam Stud. 2019 Nov;28(11):3121-3131 Authors: Watson RJ, Rose HA, Doull M, Adjei J, Saewyc E

Article GUID: 31649475


National Partnership for Maternal Safety: Consensus Bundle on Venous Thromboembolism.

Author(s): Urato AC, Abi-Jaoude E, Abramson J, Alter H, Andrew LB, Antonuccio D, Bero L, Biron P, Boylan LS, Braillon A, Brophy JM, Brownlee S, Cassels A, Cook-Deegan R, Cosgrove L, De Fiore L, Deyo RA, Elshaug A, Farquhar C, Fatovich DM, Fingerman ...

Obstet Gynecol. 2019 Nov;134(5):1115-1117 Authors: Urato AC, Abi-Jaoude E, Abramson J, Alter H, Andrew LB, Antonuccio D, Bero L, Biron P, Boylan LS, Braillon A, Brophy JM, Brownlee S, Cassels A, Cook-Deegan R, Cosgrove L, De Fiore L, Deyo RA, Elshaug A, Farquhar C, Fatovich DM, Fingerman E, G ...

Article GUID: 31651818


Computer-Aided Diagnosis System of Alzheimer's Disease Based on Multimodal Fusion: Tissue Quantification Based on the Hybrid Fuzzy-Genetic-Possibilistic Model and Discriminative Classification Based on the SVDD Model.

Author(s): Lazli L, Boukadoum M, Ait Mohamed O

Brain Sci. 2019 Oct 22;9(10): Authors: Lazli L, Boukadoum M, Ait Mohamed O

Article GUID: 31652635


Understanding Events by Eye and Ear: Agent and Verb Drive Non-anticipatory Eye Movements in Dynamic Scenes.

Author(s): de Almeida RG, Di Nardo J, Antal C, von Grünau MW

Front Psychol. 2019;10:2162 Authors: de Almeida RG, Di Nardo J, Antal C, von Grünau MW

Article GUID: 31649574


Drude polarizable force field for cation-π interactions of alkali and quaternary ammonium ions with aromatic amino acid side chains

Author(s): Orabi EA; Davis RL; Lamoureux G;

Cation-p interactions play important roles in molecular recognition and in the stability and function of proteins. However, accurate description of the structure and energetics of cation-p interactions presents a challenge to both additive and polarizable force fields, which are rarely designed to account for the complexation of charged groups with aromat ...

Article GUID: 31652004


Novel highly potent OXE receptor antagonists with prolonged plasma lifetimes that are converted to active metabolites in vivo in monkeys.

Author(s): Ye Q, Chourey S, Reddy CN, Wang R, Cossette C, Gravel S, Slobodchikova I, Vuckovic D, Rokach J, Powell WS

Br J Pharmacol. 2019 Oct 26;: Authors: Ye Q, Chourey S, Reddy CN, Wang R, Cossette C, Gravel S, Slobodchikova I, Vuckovic D, Rokach J, Powell WS

Article GUID: 31655025


Mechanisms by which PE21, an extract from the white willow Salix alba, delays chronological aging in budding yeast.

Author(s): Medkour Y, Mohammad K, Arlia-Ciommo A, Svistkova V, Dakik P, Mitrofanova D, Rodriguez MEL, Junio JAB, Taifour T, Escudero P, Goltsios FF, Soodbakhsh S, Maalaoui H, Simard É, Titorenko VI

Oncotarget. 2019 Oct 08;10(56):5780-5816 Authors: Medkour Y, Mohammad K, Arlia-Ciommo A, Svistkova V, Dakik P, Mitrofanova D, Rodriguez MEL, Junio JAB, Taifour T, Escudero P, Goltsios FF, Soodbakhsh S, Maalaoui H, Simard É, Titorenko VI

Article GUID: 31645900


Fos expression is increased in oxytocin neurons of female rats with a sexually conditioned mate preference for an individual male rat.

Author(s): Mac Cionnaith CE, Lemay A, Gomez-Perales EL, Robert G, Cernik R, Brake W, Pfaus JG

Horm Behav. 2019 Oct 21;:104612 Authors: Mac Cionnaith CE, Lemay A, Gomez-Perales EL, Robert G, Cernik R, Brake W, Pfaus JG

Article GUID: 31647923


Population variation in density-dependent growth, mortality and their trade-off in a stream fish.

Author(s): Matte JM, Fraser DJ, Grant JWA

J Anim Ecol. 2019 Oct 23;: Authors: Matte JM, Fraser DJ, Grant JWA

Article GUID: 31642512


Life after breast cancer: moving on, sitting down or standing still? A prospective study of Canadian breast cancer survivors.

Author(s): Sabiston CM, Wrosch C, Fong AJ, Brunet J, Gaudreau P, O'Loughlin J, Meterissian S

BMJ Open. 2018 07 28;8(7):e021770 Authors: Sabiston CM, Wrosch C, Fong AJ, Brunet J, Gaudreau P, O'Loughlin J, Meterissian S

Article GUID: 30056387


Cyst Reduction in a Polycystic Kidney Disease Drosophila Model Using Smac Mimics.

Author(s): Millet-Boureima C, Chingle R, Lubell WD, Gamberi C

Biomedicines. 2019 Oct 18;7(4): Authors: Millet-Boureima C, Chingle R, Lubell WD, Gamberi C

Article GUID: 31635379


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