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Phase Diagram for a Lysyl-Phosphatidylglycerol Analogue in Biomimetic Mixed Monolayers with Phosphatidylglycerol: Insights into the Tunable Properties of Bacterial Membranes.

Author(s): Wölk C, Youssef H, Guttenberg T, Marbach H, Vizcay-Barrena G, Shen C, Brezesinski G, Harvey RD

Ion pairing between the major phospholipids of the Staphylococcus aureus plasma membrane (phosphatidylglycerol - PG and lysyl-phosphatidylglycerol - LPG) confers resistance to antimicrobial peptides and other antibiotics. We developed 3adLPG, a stable synthetic analogue which can substitute for t ...

Article GUID: 32065707


Modeling Shows that Rotation about the Peroxide O-O Bond Assists Protein and Lipid Functional Groups in Discriminating between H2O2 and H2O

Author(s): Orabi EA; English AM;

Long associated with cell death, hydrogen peroxide (H2O2) is now known to perform many physiological roles. Unraveling its biological mechanisms of action requires atomic-level knowledge of its association with proteins and lipids, which we address here. High-level [MP2(full)/6-311++G(3df,3pd)] ab initio calculations reveal skew rotamers as the lowest-ene ...

Article GUID: 33356279


PASS: A Multimodal Database of Physical Activity and Stress for Mobile Passive Body/ Brain-Computer Interface Research

Author(s): Parent M; Albuquerque I; Tiwari A; Cassani R; Gagnon JF; Lafond D; Tremblay S; Falk TH;

With the burgeoning of wearable devices and passive body/brain-computer interfaces (B/BCIs), automated stress monitoring in everyday settings has gained significant attention recently, with applications ranging from serious games to clinical monitoring. With mobile users, however, challenges arise due to other overlapping (and potentially confounding) phy ...

Article GUID: 33363449


PM2.5 and hospital admissions among Medicare enrollees with chronic debilitating brain disorders.

Author(s): Yitshak-Sade M, Nethery R, Schwartz JD, Mealli F, Dominici F, Di Q, Abu Awad Y, Ifergane G, Zanobetti A

BACKGROUND: Although long-term exposure to particulate matter METHODS: We constructed daily zipcode counts of hospital admissions of Medicare beneficiaries older than 65 across the United-States (2000-2014). We obtained daily PM2.5 estimates from a satellite-based model. A propensity score matchi ...

Article GUID: 33065503


Integrative approach for detecting membrane proteins.

Author(s): Alballa M, Butler G

BACKGROUND: Membrane proteins are key gates that control various vital cellular functions. Membrane proteins are often detected using transmembrane topology prediction tools. While transmembrane topology prediction tools can detect integral membrane proteins, they do not address surface-bound proteins. In this study, we focused on finding the best techniq ...

Article GUID: 33349234


Call for Special Issue Papers: Programming Models and Algorithms for Big Data.

Author(s): Al-Turjman F, Hamouda W, Mumtaz S

Big Data. 2020 Dec; 8(6):542-543 Authors: Al-Turjman F, Hamouda W, Mumtaz S PMID: 33347369 [PubMed - as supplied by publisher]

Article GUID: 33347369


Inter-protein residue covariation information unravels physically interacting protein dimers

Author(s): Salmanian S; Pezeshk H; Sadeghi M;

Background: Predicting physical interaction between proteins is one of the greatest challenges in computational biology. There are considerable various protein interactions and a huge number of protein sequences and synthetic peptides with unknown interacting counterparts. Most of co-evolutionary methods discover a combination of physical interplays and f ...

Article GUID: 33334319


WAUC: A Multi-Modal Database for Mental Workload Assessment Under Physical Activity

Author(s): Albuquerque I; Tiwari A; Parent M; Cassani R; Gagnon JF; Lafond D; Tremblay S; Falk TH;

Assessment of mental workload is crucial for applications that require sustained attention and where conditions such as mental fatigue and drowsiness must be avoided. Previous work that attempted to devise objective methods to model mental workload were mainly based on neurological or physiological data collected when the participants performed tasks that ...

Article GUID: 33335465


Work Fatigue Profiles: Nature, Implications, and Associations With Psychological Empowerment.

Author(s): Blais AR, Gillet N, Houle SA, Comeau CA, Morin AJS

The present study examined the distinct configurations, or profiles, taken by work fatigue dimensions among samples of military (n = 1,436) and civilian (n = 2,477) employees. We also tested profile similarity across these two samples of employees. In addition, this research documented the relations between the identified work fatigue profiles, one predic ...

Article GUID: 33329261


Pantomime (Not Silent Gesture) in Multimodal Communication: Evidence From Children's Narratives.

Author(s): Marentette P, Furman R, Suvanto ME, Nicoladis E

Pantomime has long been considered distinct from co-speech gesture. It has therefore been argued that pantomime cannot be part of gesture-speech integration. We examine pantomime as distinct from silent gesture, focusing on non-co-speech gestures that occur in the midst of children's spoken narratives. We propose that gestures with features of pantomi ...

Article GUID: 33329222


Near native-like stress pattern perception in English-French bilinguals as indexed by the mismatch negativity.

Author(s): Gilbert AC, Honda CT, Phillips NA, Baum SR

We examined lexical stress processing in English-French bilinguals. Auditory mismatch negativity (MMN) responses were recorded in response to English and French pseudowords, whose primary stress occurred either on a language-consistent "usual" or language-inconsistent "unusual" syllable. In most conditions, the pseudowords elicited two consecutive MMNs, a ...

Article GUID: 33333337


"Was I asking for it?": An experimental investigation of perceived responsibility, mental contamination and workplace sexual harassment.

Author(s): Krause S, Radomsky AS

BACKGROUND AND OBJECTIVES: Mental contamination (i.e., contamination concerns that arise in the absence of direct contact with a contaminant) is a common symptom in obsessive-compulsive disorder (OCD). Cognitive theories suggest that it results from individuals' misinterpretations of perceived violations. Cognitive theories of OCD also highlight the i ...

Article GUID: 33321247


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