Author(s): Selvaraj G; Kaliamurthi S; Peslherbe GH; Wei DQ;

ackground: Coronavirus (CoV) is an emerging human pathogen causing severe acute respiratory syndrome (SARS) around the world. Earlier identification of biomarkers for SARS can facilitate detection and reduce the mortality rate of the disease. Thus, by integrated network analysis and structural modeling approach, we aimed to explore the potential drug targ ...

Article GUID: 33968364

Author(s): Tremblay SA; Jäger AT; Huck J; Giacosa C; Beram S; Schneider U; Grahl S; Villringer A; Tardif CL; Bazin PL; Steele CJ; Gauthier CJ;

Efficient neural transmission is crucial for optimal brain function, yet the plastic potential of white matter (WM) has long been overlooked. Growing evidence now shows that modifications to axons and myelin occur not only as a result of long-term learning, but also after short training periods. ...

Article GUID: 33885965

Author(s): Costa ACBP; Omran RP; Law C; Dumeaux V; Whiteway M;

Candida albicans opaque cells release pheromones to stimulate cells of opposite mating type to activate their pheromone response pathway. Although this fungal pathogen shares orthologous proteins involved in the process with Saccharomyces cerevisiae, the pathway in each organism has unique characteristics. We have used GFP-tagged fusion proteins to invest ...

Article GUID: 33793759

Author(s): Pothier K; Vrinceanu T; Intzandt B; Bosquet L; Karelis AD; Lussier M; Vu TTM; Nigam A; Li KZH; Berryman N; Bherer L;

Objectives: Mobility is a complex but crucial clinical outcome in older adults. Past observational studies have highlighted that cardiorespiratory fitness (CRF), energy cost of walking (ECW), and cognitive switching abilities are associated with mobility performance, making these key determinants ...

Article GUID: 33774144

Author(s): Machado A; Cai Z; Vincent T; Pellegrino G; Lina JM; Kobayashi E; Grova C;

In functional near infrared spectroscopy (fNIRS), deconvolution analysis of oxy and deoxy-hemoglobin concentration changes allows estimating specific hemodynamic response functions (HRF) elicited by neuronal activity, taking advantage of the fNIRS excellent temporal resolution. Diffuse optical tomography (DOT) is also becoming the new standard reconstruct ...

Article GUID: 33727581

Author(s): Masoumi N; Belasso CJ; Ahmad MO; Benali H; Xiao Y; Rivaz H;

Purpose: Accurate multimodal registration of intraoperative ultrasound (US) and preoperative computed tomography (CT) is a challenging problem. Construction of public datasets of US and CT images can accelerate the development of such image registration techniques. This can help ensure the accuracy and safety of spinal surgeries using image-guided surgery ...

Article GUID: 33683544

Author(s): Zhang X; Wasson MC; Shayan M; Berdichevsky EK; Ricardo-Noordberg J; Singh Z; Papazyan EK; Castro AJ; Marino P; Ajoyan Z; Chen Z; Islamoglu T; Howarth AJ; Liu Y; Majewski MB; Katz MJ; Mondloch JE; Farha OK;

Porphyrins are important molecules widely found in nature in the form of enzyme active sites and visible light absorption units. Recent interest in using these functional molecules as building blocks for the construction of metal-organic frameworks (MOFs) have rapidly increased due to the ease in ...

Article GUID: 33678810

Author(s): Jeancolas L; Petrovska-Delacrétaz D; Mangone G; Benkelfat BE; Corvol JC; Vidailhet M; Lehéricy S; Benali H;

Many articles have used voice analysis to detect Parkinson's disease (PD), but few have focused on the early stages of the disease and the gender effect. In this article, we have adapted the latest speaker recognition system, called x-vectors, in order to detect PD at an early stage using voi ...

Article GUID: 33679361

Author(s): Park JH, Kim YU, Jeon J, Yun BY, Kang Y, Kim S

This study suggests a new perspective of biochar as a building material that improve not only for the strength but also hygrothermal properties. Biochar has a high porosity and surface area created by pyrolysis. It can be suitably used as a porous material because porous materials are used by incorporating into building materials for improving hygrotherma ...

Article GUID: 33611181

Author(s): Tat J, Crawford J, Chong J, Powell T, Fevens TG, Popa T, Martineau PA

Purpose: To dynamically assess for Hill-Sachs engagement with animated 3-dimensional (3D) shoulder models. Methods: We created 3D shoulder models from reconstructed computed tomography (CT) images from a consecutive series of patients with recurrent anterior dislocation. They were divided into 2 groups based on the perceived Hill-Sachs severity. For our c ...

Article GUID: 33615252

Author(s): Millera Ferriz L, Ponton DE, Storck V, Leclerc M, Bilodeau F, Walsh DA, Amyot M

Run-of-river power plants (RoRs) are expected to triple in number over the next decades in Canada. These structures are not anticipated to considerably promote the mobilization and transport of mercury (Hg) and its subsequent microbial transformation to methylmercury (MeHg), a neurotoxin able to biomagnify in food webs up to humans. To test whether constr ...

Article GUID: 33609815

Author(s): Danieles PK; Ybarra M; Van Hulst A; Barnett TA; Mathieu MÈ; Kakinami L; Drouin O; Bigras JL; Henderson M;

Introduction: Attrition in pediatric weight management programs is notoriously high. Greater understanding of its determinants is needed to inform retention strategies. We identified determinants of attrition in CIRCUIT, a healthy lifestyle intervention program for youth at risk of cardiovascular ...

Article GUID: 33608233