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Disposable masks release microplastics to the aqueous environment with exacerbation by natural weathering

Author(s): Wang Z; An C; Chen X; Lee K; Zhang B; Feng Q;

The COVID-19 pandemic has driven explosive growth in the use of masks has resulted in many issues related to the disposal and management of waste masks. As improperly disposed masks enter the ocean, the risk to the marine ecological system is further aggravated, especially in the shoreline environment. The objective of this study is to explore the changin ...

Article GUID: 34015713


Code-switching in parents' everyday speech to bilingual infants

Author(s): Kremin LV; Alves J; Orena AJ; Polka L; Byers-Heinlein K;

Code-switching is a common phenomenon in bilingual communities, but little is known about bilingual parents' code-switching when speaking to their infants. In a pre-registered study, we identified instances of code-switching in day-long at-home audio recordings of 21 French-English bilingual families in Montreal, Canada, who provided recordings when t ...

Article GUID: 34006344


Lateral Position-Dependent Velocity Estimation Error in Plane-Wave Doppler Ultrasound Systems

Author(s): Wei L; Williams R; Loupas T; Helfield B; Burns PN;

Doppler ultrasound has become a standard method used to diagnose and grade vascular diseases and monitor their progression. Conventional focused-beam color Doppler imaging is routinely used in clinical practice, but suffers from inherent trade-offs between spatial, temporal and velocity resolution. Newer, plane-wave Doppler imaging offers rapid simultaneo ...

Article GUID: 34006440


Tools and Techniques for Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)/COVID-19 Detection

Author(s): Safiabadi Tali SH; LeBlanc JJ; Sadiq Z; Oyewunmi OD; Camargo C; Nikpour B; Armanfard N; Sagan SM; Jahanshahi-Anbuhi S;

The coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory disease coronavirus 2 (SARS-CoV-2), has led to millions of confirmed cases and deaths worldwide. Efficient diagnostic tools are in high demand, as rapid and large-scale testing plays a pivotal role in patient man ...

Article GUID: 33980687


Caloric restriction creates a metabolic pattern of chronological aging delay that in budding yeast differs from the metabolic design established by two other geroprotectors

Author(s): Mohammad K; Titorenko VI;

Caloric restriction and the tor1? mutation are robust geroprotectors in yeast and other eukaryotes. Lithocholic acid is a potent geroprotector in Saccharomyces cerevisiae. Here, we used liquid chromatography coupled with tandem mass spectrometry method of non-targeted metabolomics to compare the effects of these three geroprotectors on the intracellular m ...

Article GUID: 33868583


Calcium-calcineurin signaling pathway in Candida albicans: A potential drug target

Author(s): Li W; Shrivastava M; Lu H; Jiang Y;

Increased morbidity and mortality of candidiasis are a notable threat to the immunocompromised patients. At present, the types of drugs available to treat C. albicans infection are relatively limited. Moreover, the emergence of antifungal drug resistance of C. albicans makes the treatment of C. albicans infection more difficult. The calcium-calcineurin si ...

Article GUID: 33989979


Beyond ribose and phosphate: Selected nucleic acid modifications for structure-function investigations and therapeutic applications

Author(s): Liczner C; Duke K; Juneau G; Egli M; Wilds CJ;

Over the past 25 years, the acceleration of achievements in the development of oligonucleotide-based therapeutics has resulted in numerous new drugs making it to the market for the treatment of various diseases. Oligonucleotides with alterations to their scaffold, prepared with modified nucleosides and solid-phase synthesis, have yielded molecules with in ...

Article GUID: 33981365


Indoor airborne disinfection with electrostatic disinfector (ESD): Numerical simulations of ESD performance and reduction of computing time

Author(s): Feng Z; Cao SJ; Wang J; Kumar P; Haghighat F;

Airborne transmissions of infectious disease (e.g. SARS-CoV-2) in indoor environments may induce serious threat to public health. Air purification devices are necessary to remove and/or inactivate airborne biological species from indoor air environment. Corona discharge in an electrostatic precipitator is capable of removing particulate matter and disinfe ...

Article GUID: 33994653


Macromolecularly Engineered Thermoreversible Heterogeneous Self-Healable Networks Encapsulating Reactive Multidentate Block Copolymer-Stabilized Carbon Nanotubes

Author(s): Zhang G; Patel T; Nellepalli P; Bhagat S; Hase H; Jazani AM; Salzmann I; Ye Z; Oh JK;

The development of heterogeneous covalent adaptable networks (CANs) embedded with carbon nanotubes (CNTs) that undergo reversible dissociation/recombination through thermoreversibility has been significantly explored. However, the carbon nanotube (CNT)-incorporation methods based on physical mixing and chemical modification could result in either phase se ...

Article GUID: 33988899


Alpha and beta neural oscillations differentially reflect age-related differences in bilateral coordination

Author(s): Shih PC; Steele CJ; Nikulin VV; Gundlach C; Kruse J; Villringer A; Sehm B;

Bilateral in-phase (IP) and anti-phase (AP) movements represent two fundamental modes of bilateral coordination that are essential for daily living. Although previous studies have shown that aging is behaviorally associated with decline in bilateral coordination, especially in AP movements, the underlying neural mechanisms remain unclear. Here, we use kin ...

Article GUID: 33979705


Effector-independent brain network for auditory-motor integration: fMRI evidence from singing and cello playing

Author(s): Segado M; Zatorre RJ; Penhune VB;

Many everyday tasks share high-level sensory goals but differ in the movements used to accomplish them. One example of this is musical pitch regulation, where the same notes can be produced using the vocal system or a musical instrument controlled by the hands. Cello playing has previously been shown to rely on brain structures within the singing network ...

Article GUID: 33989814


Loss of function of the carbon catabolite repressor CreA leads to low but inducer-independent expression from the feruloyl esterase B promoter in Aspergillus niger

Author(s): Reijngoud J; Arentshorst M; Ruijmbeek C; Reid I; Alazi ED; Punt PJ; Tsang A; Ram AFJ;

Objective: With the aim to decipher the mechanisms involved in the transcriptional regulation of feruloyl esterase encoded by faeB, a genetic screen was performed to isolate A. niger mutants displaying inducer-independent expression from the faeB promoter. Result: PfaeB-amdS and PfaeB-lux dual reporter strains were constructed and used to isolate trans-a ...

Article GUID: 33738610


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