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Economizing the lignocellulosic hydrolysis process using heterologously expressed auxiliary enzymes feruloyl esterase D (CE1) and β-xylosidase (GH43) derived from thermophilic fungi Scytalidium thermophilum

Author(s): Agrawal D; Tsang A; Chadha BS;

Two lignocellulolytic accessory enzymes, feruloyl esterase D (FAED_SCYTH) and ß-xylosidase (XYL43B_SCYTH) were cloned and produced in the Pichia pastoris X33 as host. The molecular weight of recombinant enzymes FAED_SCYTH and XYL43B_SCYTH were ~ 31 and 40 kDa, respectively. FAED_SCYTH showed optimal activity at pH 6.0, 60 °C; and XYL43B_SCYTH at pH 7.0, 5 ...

Article GUID: 34293687


Do the Consequences Experienced by the People in the Life of a Problem Gambler Differ Based on the Nature of Their Relationship with the Gambler?

Author(s): Ferland F; Blanchette-Martin N; Côté M; Tremblay J; Kairouz S; Nadeau L; Savard AC; L' Espérance N; Dufour M;

Consequences experienced by the partners of individuals with a gambling disorder are well documented. However, little is known about the deleterious effects experienced by other people than partners of gamblers. A better understanding of these consequences could help improve clinical practices. T ...

Article GUID: 34286413


Multiphase CFD simulation of the nearshore spilled oil behaviors

Author(s): Raznahan M; An C; Li SS; Geng X; Boufadel M;

Oil spills are a serious environmental problem. To better support risk assessment and pollution control for oil spills, a good understanding of oil transport in the environment is required. This study focused on the numerical simulation of the nearshore oil behaviors based on computational fluid dynamics. Based on the Navier-Stokes momentum equations for ...

Article GUID: 34284211


PSON: A Serialization Format for IoT Sensor Networks

Author(s): Luis Á; Casares P; Cuadrado-Gallego JJ; Patricio MA;

In many Internet of Things (IoT) environments, the lifetime of a sensor is linked to its power supply. Sensor devices capture external information and transmit it. They also receive messages with control commands, which means that one of the largest computational overheads of sensor devices is spent on data serialization and deserialization tasks, as well ...

Article GUID: 34283115


A polygenic score for acute vaso-occlusive pain in pediatric sickle cell disease

Author(s): Rampersaud E; Kang G; Palmer LE; Rashkin SR; Wang S; Bi W; Alberts NM; Anghelescu D; Barton M; Birch K; Boulos N; Brandow AM; Brooke RJ; Chang TC; Chen W; Cheng Y; Ding J; Easton J; Hodges JR; Kanne CK; Levy S; Mulder H; Patel AP; Puri L ...

Individuals with monogenic disorders can experience variable phenotypes that are influenced by genetic variation. To investigate this in sickle cell disease (SCD), we performed whole-genome sequencing (WGS) of 722 individuals with hemoglobin HbSS or HbSß0-thalassemia from Baylor College of Medici ...

Article GUID: 34283174


A photo-Fenton nanocomposite ultrafiltration membrane for enhanced dye removal with self-cleaning properties

Author(s): Yue R; Raisi B; Rahmatinejad J; Ye Z; Barbeau B; Rahaman MS;

Membrane fouling is an ongoing challenge in the membrane filtration process. Herein, a photocatalytic membrane comprising a reactive layer was fabricated by engineering partially reduced graphene oxide/Ag nanoparticles/MIL-88A (prGO/Ag/M88A, pGAM) photocatalysts on the PVDF substrate membranes. Benefiting from the high conductivity of prGO and the surface ...

Article GUID: 34273782


Assessing the coastal sensitivity to oil spills from the perspective of ecosystem services: A case study for Canada's pacific coast

Author(s): Feng Q; An C; Chen Z; Owens E; Niu H; Wang Z;

Coastal environment is one of the most important ecological and socioeconomic areas. However, increasing energy demand and economic development lead to a continuous gas and oil exploration, production, and traffics, which notably raise the risk of oil spill accidents in coastal areas. Sensitivity assessment aiming to determine the coastal features that wo ...

Article GUID: 34271360


Personal Social Networks and Adiposity in Adolescents: A Feasibility Study

Author(s): Ybarra M; Barnett TA; Yu J; Van Hulst A; Drouin O; Kakinami L; Saint-Charles J; Henderson M;

i>Background and Objective: Weight-related behaviors are determined by multiple individual and contextual factors, with recent evidence implicating personal social networks (PSNs). Greater understanding of these relationships could help inform healthy weight promoting interventions. We conducted ...

Article GUID: 34264758


COVID-19 virtual patient cohort suggests immune mechanisms driving disease outcomes

Author(s): Jenner AL; Aogo RA; Alfonso S; Crowe V; Deng X; Smith AP; Morel PA; Davis CL; Smith AM; Craig M;

To understand the diversity of immune responses to SARS-CoV-2 and distinguish features that predispose individuals to severe COVID-19, we developed a mechanistic, within-host mathematical model and virtual patient cohort. Our results suggest that virtual patients with low production rates of infe ...

Article GUID: 34260666


Development and Validation of a Multi-informant Measure of Social Behaviors for Youth with Intellectual Disabilities

Author(s): Olivier E; Morin AJS; Tracey D; Verma N; Dubé C; Gagnon C; Craven RG; Maïano C;

Youth with intellectual disability (ID) are at an increased risk of displaying fewer prosocial behaviors and more numerous aggressive behaviors in various environments. This study proposes a new multi-informant (youth, teachers, and parents) measure of social behaviors for youth with ID. The sample includes 348 youth with mild (51.41%) and moderate (48.59 ...

Article GUID: 34255229


Formation of oil-particle aggregates: Impacts of mixing energy and duration

Author(s): Ji W; Boufadel M; Zhao L; Robinson B; King T; An C; Zhang BH; Lee K;

Spilled oil slicks are likely to break into droplets offshore due to wave energy. The fate and transport of such droplets are affected by suspended particles in local marine environment, through forming oil particle aggregates (OPAs). OPA formation is affected by various factors, including the mixing energy and duration. To evaluate these two factors, lab ...

Article GUID: 34252767


Ethnoracial Differences in Coercive Referral and Intervention Among Patients With First-Episode Psychosis

Author(s): Knight S; Jarvis GE; Ryder AG; Lashley M; Rousseau C;

Objective: Using a retrospective sample, the authors sought to determine whether Black patients with first-episode psychosis (FEP) in Canada were at a higher risk for coercive referral and coercive intervention than non-Black patients with FEP. Methods: Retrospective data from patients referred to an FEP program in 2008-2018 were collected via chart revi ...

Article GUID: 34253035


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