Author(s): Bathini S; Pakkiriswami S; Ouellette RJ; Ghosh A; Packirisamy M;
Extracellular vesicles (EVs) are the cell-derived vesicles which play a critical role in cell-to-cell communication, and disease progression. These vesicles contain a myriad of substances like RNA, DNA, proteins, and lipids from their origin cells, offering a good source of biomarkers. The existing methods for the isolation of EVs are time-consuming, lack ...
Article GUID: 34517262
Author(s): Davis AN; Samlali K; Kapadia JB; Perreault J; Shih SCC; Kharma N;
In this paper, we describe the design and performance of two digital microfluidics (DMF) chips capable of executing multiple ribozymatic reactions, with proper controls, in response to short single-stranded DNA inducers. Since the fluorescence output of a reaction is measurable directly from the chip, without the need for gel electrophoresis, a complete e ...
Article GUID: 34514224
Author(s): Wang J; Huang JJ; Mulligan C;
Humans who are exposed to metals in road dust may have potential health risks through touching, ingesting, and inhaling the suspended road dust. There were limited studies to link seasonal emission sources to health risks from metals in road dust. In this study, metals in road dust from different functional areas were seasonally monitored. The contributio ...
Article GUID: 34510345
Author(s): Messina C; Ottenwaelder X; Forgione P;
Herein, we report a modular synthetic route to access tetra-arylated thiophene compounds with four different substituents with programmed chemical control provided by an ester activating/directing group. This method enables the functionalization of individual positions of thiophene sequentially via regioselective halogenations and cross-coupling reactions ...
Article GUID: 34506149
Author(s): Christopher T Richard
This paper aims to design lattice structures for rapid-investment casting (RIC), and the goal of the design methodology is to minimize casting defects that are related to the lattice topology. RIC can take full advantage of the unprecedented design freedom provided by AM. Since design for RIC has multiple objectives, we limit our study to lattice structur ...
Article GUID: 34500961
Author(s): Sohrabi Kashani A; Packirisamy M;
With the advancement of nanotechnology, the nano-bio-interaction field has emerged. It is essential to enhance our understanding of nano-bio-interaction in different aspects to design nanomedicines and improve their efficacy for therapeutic and diagnostic applications. Many researchers have extensively studied the toxicological responses of cancer cells t ...
Article GUID: 34502495
Author(s): Watkins-Martin K; Orri M; Pennestri MH; Castellanos-Ryan N; Larose S; Gouin JP; Ouellet-Morin I; Chadi N; Philippe F; Boivin M; Tremblay RE; Côté S; Geoffroy MC;
Background: Concerns have been raised that the COVID-19 pandemic could increase risk for adverse mental health outcomes, especially in young adults, a vulnerable age group. We investigated changes in depression and anxiety symptoms (overall and severe) from before to during the pandemic, as well ...
Article GUID: 34496901
Author(s): Gervais CLM; Johnston MS;
When a youth sexually offends, most of the reactions and repercussions that follow are understandably negative. However, there is limited research about mixed reactions involving remorse and responsibility on the part of the adolescent who offended and their relatives. Based on qualitative interviews with 16 caregivers among 10 families in Canada, this ar ...
Article GUID: 34490799
Author(s): Reilly RC; Lee V; Laux K; Robitaille A;
Objectives: This article presents the findings of a pilot study situated in a tertiary care cancer centre and examines the impact of an art therapy group on the experiences of women living through breast cancer. Study design: The study design used in this study is a qualitative cross-case comparative case. Methods: Ten women were interviewed about their ...
Article GUID: 34487868
Author(s): Schott E; Mastroberardino M; Fourakis E; Lew-Williams C; Byers-Heinlein K;
The ability to differentiate between two languages sets the stage for bilingual learning. Infants can discriminate languages when hearing long passages, but language switches often occur on short time scales with few cues to language identity. As bilingual infants begin learning sequences of sounds and words, how do they detect the dynamics of two languag ...
Article GUID: 34482624
Author(s): Savard M; Michaelsen S;
Background: During the civil war in northern Uganda (1986-2006), thousands of girls were abducted into rebel and government forces. Most of the females who were not abducted lived in abhorrent conditions in camps for internally displaced people (IDP). As the war was drawing to a close, reintegration programs emerged and some continue today. Objective: Us ...
Article GUID: 34479000
Author(s): Song Y; Lu M; Mandl GA; Xie Y; Sun G; Chen J; Liu X; Capobianco JA; Sun L;
Modulating the emission wavelengths of materials has always been a primary focus of fluorescence technology. Nanocrystals (NCs) doped with lanthanide ions with rich energy levels can produce a variety of emissions at different excitation wavelengths. However, the control of multi-modal emissions of these ions has remained a challenge. Herein, we present a ...
Article GUID: 34476872
