Author(s): Pride T; Lam A; Swansburg J; Seno M; Lowe MB; Bomfim E; Toombs E; Marsan S; LoRusso J; Roy J; Gurr E; LaFontaine J; Paul J; Burack JA; Mushquash C; Stewart SH; Wendt DC;

Indigenous Peoples experience disproportionately higher rates of problematic substance use. These problems are situated in a context of individual and intergenerational trauma from colonization, residential schools, and racist and discriminatory practices, policies, and services. Therefore, subst ...

Article GUID: 34895091

Author(s): Hudson CJ; Groh AMR; Macciardi F; Hudson RC;

No abstract

Article GUID: 34889025

Author(s): Atoba K; Newman G; Brody S; Highfield W; Kim Y; Juan A;

Rising flood damages have prompted local communities to implement buyout and property acquisition programmes to eliminate repetitive losses for at-risk properties. However, buyouts are often costly to implement and are reactionary solutions to flooding. This study quantifies the benefits of acquiring vacant private properties in flood-prone areas rather t ...

Article GUID: 34887609

Author(s): Lee K; Revelli M; Dickson D; Marier P;

Policy makers, practitioners, and scholars are increasingly examining the types of care services (formal vs. informal) offered to older adults. This study evaluates predictors of these adults' preferences for care types in Québec, Canada, based on a province-wide survey inserted in a magazine of the largest seniors' club in Canada (FADOQ). More th ...

Article GUID: 34886702

Author(s): Jaunky DB; Larocque K; Husser MC; Liu JT; Forgione P; Piekny A;

We reveal the effects of a new microtubule-destabilizing compound in human cells. C75 has a core thienoisoquinoline scaffold with several functional groups amenable to modification. Previously we found that sub micromolar concentrations of C75 caused cytotoxicity. We also found that C75 inhibited microtubule polymerization and competed with colchicine for ...

Article GUID: 34880347

Author(s): Lennox CB; Do JL; Crew JG; Arhangelskis M; Titi HM; Howarth AJ; Farha OK; Frišcic T;

Mechanochemistry enables rapid access to boron imidazolate frameworks (BIFs), including ultralight materials based on Li and Cu(i) nodes, as well as new, previously unexplored systems based on Ag(i) nodes. Compared to solution methods, mechanochemistry is faster, provides materials with improved porosity, and replaces harsh reactants (e.g. n-butylithium) ...

Article GUID: 34881001

Author(s): Villaruel FR; Martins M; Chaudhri N;

The capacity to suppress learned responses is essential for animals to adapt in dynamic environments. Extinction is a process by which animals learn to suppress conditioned responding when an expected outcome is omitted. The infralimbic cortex (IL) to nucleus accumbens shell (NAcS) neural circuit is implicated in suppressing conditioned responding after e ...

Article GUID: 34880119

Author(s): Harel D; Levis B; Sun Y; Fischer F; Ioannidis JPA; Cuijpers P; Patten SB; Ziegelstein RC; Markham S; Benedetti A; Thombs BD;

Shortened versions of self-reported questionnaires may be used to reduce respondent burden. When shortened screening tools are used, it is desirable to maintain equivalent diagnostic accuracy to full-length forms. This manuscript presents a case study that illustrates how external data and indivi ...

Article GUID: 34780986

Author(s): Huelsnitz CO; Jones RE; Simpson JA; Joyal-Desmarais K; Standen EC; Auster-Gussman LA; Rothman AJ;

Relationship partners affect one another's health outcomes through their health behaviors, yet how this occurs is not well understood. To fill this gap, we present the Dyadic Health Influence Model (DHIM). The DHIM identifies three routes through which a person (the agent) can impact the heal ...

Article GUID: 34873983

Author(s): Corminboeuf A; Montero-Serrano JC; St-Louis R; Dalpé A; Gélinas Y;

The concentrations of 23 polycyclic aromatic hydrocarbons (PAHs; 16 parent PAHs and 7 alkyl-PAHs) were determined in 45 surface sediment and 7 basal sediment box core samples retrieved from the Estuary and Gulf of St. Lawrence in eastern Canada. The concentration sums of 16 priority PAHs (S₁₆PAHs) in the surface sediments (represent ...

Article GUID: 34871900

Author(s): Goldfield GS; Walsh J; Sigal RJ; Kenny GP; Hadjiyannakis S; De Lisio M; Ngu M; Prud' homme D; Alberga AS; Doucette S; Goldfield DB; Cameron JD;

The brain-derived neurotrophic factor (BDNF) Val66Met polymorphism is functionally related to BDNF, and is associated with obesity and metabolic complications in adults, but limited research exists among adolescents. This study comparatively examined carriers and non-carriers of the BDNF Val66Met ...

Article GUID: 34867148

Author(s): Pallikaras V; Carter F; Velazquez-Martinez DN; Arvanitogiannis A; Shizgal P;

Optogenetic experiments reveal functional roles of specific neurons. However, functional inferences have been limited by widespread adoption of a restricted set of stimulation parameters. Broader exploration of the parameter space can deepen insight into the mapping between selective neural activity and behavior. In this way, characteristics of the activa ...

Article GUID: 34864162