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Olfactory function reflects episodic memory performance and atrophy in the medial temporal lobe in individuals at risk for Alzheimer's disease

Author(s): Papadatos Z; Phillips NA;

We examined cognitive domains and brain regions associated with olfactory performance in cognitively unimpaired older adults (CU-OAs) and individuals with or at risk for Alzheimer's Disease (AD). We compared CU-OAs (N = 55), individuals with subjective cognitive decline (SCD, N = 55), mild cognitive impairment (MCI, N = 101), and AD (N = 45) on measur ...

Article GUID: 37146503


Adolescent anxiety and pain problems: A joint, genome-wide investigation and pathway-based analysis

Author(s): Mascheretti S; Forni D; Lampis V; Fumagalli L; Paquin S; Andlauer TFM; Wang W; Dionne G; Brendgen MR; Vitaro F; Ouellet-Morin I; Rouleau G; Gouin JP; Côté S; Tremblay RE; Turecki G; Garon-Carrier G; Boivin M; Battaglia M;

Both common pain and anxiety problems are widespread, debilitating and often begin in childhood-adolescence. Twin studies indicate that this co-occurrence is likely due to shared elements of risk, rather than reciprocal causation. A joint genome-wide investigation and pathway/network-based analys ...

Article GUID: 37146008


Cooperative Sensitization Upconversion in Solution Dispersions of Co-Crystal Assemblies of Mononuclear Yb3+ and Eu3+ Complexes

Author(s): Sun G; Xie Y; Wang Y; Mandl GA; Maurizio SL; Zhang H; Ottenwaelder X; Capobianco JA; Sun L;

Lanthanide upconversion luminescence in nanoparticles has prompted continuous breakthroughs in information storage, temperature sensing, and biomedical applications, among others. Achieving upconversion luminescence at the molecular scale is still a critical challenge in modern chemistry. In this ...

Article GUID: 37040148


Predictors of support for anti-weight discrimination policies among Canadian adults

Author(s): Levy M; Forouhar V; Edache IY; Alberga AS;

Introduction: Weight discrimination of individuals with overweight or obesity is associated with adverse mental and physical health. Weight discrimination is prevalent in many sectors such as within workplaces, where individuals with overweight and obesity are denied the same opportunities as individuals with lower weight status, regardless of performance ...

Article GUID: 37139379


Twenty-first century adaptive teaching and individualized learning operationalized as specific blends of student-centered instructional events: A systematic review and meta-analysis

Author(s): Bernard RM; Borokhovski E; Schmid RF; Waddington DI; Pickup DI;

No abstract available

Article GUID: 37131463


Medical cannabis is effective for cancer-related pain: Quebec Cannabis Registry results

Author(s): Aprikian S; Kasvis P; Vigano M; Hachem Y; Canac-Marquis M; Vigano A;

Objectives: To evaluate the safety and effectiveness of medical cannabis (MC) in reducing pain and concurrent medications in patients with cancer. Methods: This study analysed data collected from patients with cancer who were part of the Quebec Cannabis Registry. Brief Pain Inventory (BPI), revised Edmonton Symptom Assessment System (ESAS-r) questionnair ...

Article GUID: 37130724


Associations Between Cardiovascular Risk Factors and Audiometric Hearing: Findings From the Canadian Longitudinal Study on Aging

Author(s): Mick PT; Kabir R; Pichora-Fuller MK; Jones C; Moxham L; Phillips N; Urry E; Wittich W;

Objectives: The objectives of the study were to determine, among a population-based sample of Canadian adults, if risk factors for cardiovascular disease (alone and in combination) were associated with hearing loss. Cross-sectional and longitudinal associations (the latter with about 3 years of follow-up) were examined. Risk factors considered included di ...

Article GUID: 37122082


Neurophysiology, Neuropsychology, and Epilepsy, in 2022: Hills We Have Climbed and Hills Ahead. Neurophysiology in epilepsy

Author(s): Frauscher B; Bénar CG; Engel JJ; Grova C; Jacobs J; Kahane P; Wiebe S; Zjilmans M; Dubeau F;

Since the discovery of the human electroencephalogram (EEG), neurophysiology techniques have become indispensable tools in our armamentarium to localize epileptic seizures. New signal analysis techniques and the prospects of artificial intelligence and big data will offer unprecedented opportunit ...

Article GUID: 37119580


The Effect of Linker-to-Metal Energy Transfer on the Photooxidation Performance of an Isostructural Series of Pyrene-Based Rare-Earth Metal-Organic Frameworks

Author(s): Quezada-Novoa V; Titi HM; Villanueva FY; Wilson MWB; Howarth AJ;

The tetratopic linker, 1,3,6,8-tetrakis(p-benzoic acid)pyrene (H4 TBAPy) along with rare-earth (RE) ions is used for the synthesis of 9 isostructures of a metal-organic framework (MOF) with shp topology, named RE-CU-10 (RE = Y(III), Gd(III), Tb(III), Dy(III), Ho(III), Er(III), Tm(III), Yb(III), and Lu(III)). The synthesis of each RE-CU-10 analogue require ...

Article GUID: 37116124


Proteomics-based vaccine targets annotation and design of subunit and mRNA-based vaccines for Monkeypox virus (MPXV) against the recent outbreak

Author(s): Jin Y; Fayyaz A; Liaqat A; Khan A; Alshammari A; Wang Y; Gu RX; Wei DQ;

Monkeypox Virus (MPXV) is a growing public health threat with increasing cases and fatalities globally. To date, no specific vaccine or small molecule therapeutic choices are available for the treatment of MPXV disease. In this work, we employed proteomics and structural vaccinology approaches to design mRNA and multi-epitopes-based vaccines (MVC) against ...

Article GUID: 37116237


Insights into the abiotic fragmentation of biodegradable mulches under accelerated weathering conditions

Author(s): Cai M; Qi Z; Guy C; An C; Chen X; Wang Z; Feng Q;

Biodegradable mulches (BMs) can be tilled into soils to mitigate disposal and environmental problems. However, the content of biodegradable microplastics (BMPs) would increase with the addition of biodegradable macroplastics (BMaPs). The fragmented particles have a strong affinity to soil pollutants, having the potential to transfer via the terrestrial fo ...

Article GUID: 37104954


Invariant Pattern Recognition with Log-Polar Transform and Dual-Tree Complex Wavelet-Fourier Features

Author(s): Chen G; Krzyzak A;

In this paper, we propose a novel method for 2D pattern recognition by extracting features with the log-polar transform, the dual-tree complex wavelet transform (DTCWT), and the 2D fast Fourier transform (FFT2). Our new method is invariant to translation, rotation, and scaling of the input 2D pattern images in a multiresolution way, which is very importan ...

Article GUID: 37112182


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