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On the salient limitations of the methods of assembly theory and their classification of molecular biosignatures

Author(s): Uthamacumaran A; Abrahão FS; Kiani NA; Zenil H;

We demonstrate that the assembly pathway method underlying assembly theory (AT) is an encoding scheme widely used by popular statistical compression algorithms. We show that in all cases (synthetic or natural) AT performs similarly to other simple coding schemes and underperforms compared to system-related indexes based upon algorithmic probability that t ...

Article GUID: 39112510


A Review of Mathematical and Computational Methods in Cancer Dynamics

Author(s): Uthamacumaran A; Zenil H;

Cancers are complex adaptive diseases regulated by the nonlinear feedback systems between genetic instabilities, environmental signals, cellular protein flows, and gene regulatory networks. Understanding the cybernetics of cancer requires the integration of information dynamics across multidimensional spatiotemporal scales, including genetic, transcriptio ...

Article GUID: 35957879


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