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Understanding the Retention of Vaping Additives in the Lungs: Model Lung Surfactant Membrane Perturbation by Vitamin E and Vitamin E Acetate

Author(s): Taktikakis P; Côté M; Subramaniam N; Kroeger K; Youssef H; Badia A; DeWolf C;

Deviations from the normal physicochemical and functional properties of pulmonary surfactants are associated with the incidence of lung injury and other respiratory disorders. This study aims to evaluate the alteration of the 2D molecular organization and morphology of pulmonary surfactant model membranes by the electronic cigarette additives a-tocopherol ...

Article GUID: 38437623


Interactions between the Cell Membrane Repair Protein S100A10 and Phospholipid Monolayers and Bilayers

Author(s): Yan X; Kumar K; Miclette Lamarche R; Youssef H; Shaw GS; Marcotte I; DeWolf CE; Warschawski DE; Boisselier E;

Protein S100A10 participates in different cellular mechanisms and has different functions, especially at the membrane. Among those, it forms a ternary complex with annexin A2 and the C-terminal of AHNAK and then joins the dysferlin membrane repair complex. Together, they act as a platform enablin ...

Article GUID: 34339205


Phase Diagram for a Lysyl-Phosphatidylglycerol Analogue in Biomimetic Mixed Monolayers with Phosphatidylglycerol: Insights into the Tunable Properties of Bacterial Membranes.

Author(s): Wölk C, Youssef H, Guttenberg T, Marbach H, Vizcay-Barrena G, Shen C, Brezesinski G, Harvey RD

Ion pairing between the major phospholipids of the Staphylococcus aureus plasma membrane (phosphatidylglycerol - PG and lysyl-phosphatidylglycerol - LPG) confers resistance to antimicrobial peptides and other antibiotics. We developed 3adLPG, a stable synthetic analogue which can substitute for t ...

Article GUID: 32065707


Interfacial Self-Assembly of Antimicrobial Peptide GL13K into Non-Fibril Crystalline β-Sheets.

Author(s): Youssef H, DeWolf CE

Langmuir. 2020 Jan 06;: Authors: Youssef H, DeWolf CE

Article GUID: 31880463


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