Author(s): Yan X; Kumar K; Miclette Lamarche R; Youssef H; Shaw GS; Marcotte I; DeWolf CE; Warschawski DE; Boisselier E;

Protein S100A10 participates in different cellular mechanisms and has different functions, especially at the membrane. Among those, it forms a ternary complex with annexin A2 and the C-terminal of AHNAK and then joins the dysferlin membrane repair complex. Together, they act as a platform enablin ...

Article GUID: 34339205

Author(s): Yan X, Noël F, Marcotte I, DeWolf CE, Warschawski DE, Boisselier E

The dysferlin membrane repair complex contains a small complex, S100A10-annexin A2, which initiates membrane repair by recruiting the protein AHNAK to the membrane, where it interacts via binding sites in the C-terminal region. However, no molecular data are available for the membrane binding of the various proteins involved in this complex. Therefore, th ...

Article GUID: 31825630