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Hypothalamic-pituitary-adrenal axis functioning in offspring of parents with a major affective disorder: a meta-analytic review

Author(s): Serravalle L; Trespalacios F; Ellenbogen MA;

Because the offspring of parents with an affective disorder (OAD) are at high risk for developing mental disorders, and persons with an affective disorder (AD) show dysfunctional hypothalamic-pituitary-adrenal (HPA) axis activity, changes in HPA functioning in OAD might be an etiological risk factor that precedes the development of ADs. The primary aim of ...

Article GUID: 39207496


The perceived social support of parents having bipolar disorder impacts their children's mental health: a 10-year longitudinal study

Author(s): Trespalacios F; Boyle A; Serravalle L; Hodgins S; Ellenbogen MA;

Background: The offspring of parents with bipolar disorder (OBD) are at higher risk of developing psychopathology than the offspring of parents with no affective disorder (control). In addition to genetic predisposition, childhood adversity and a stressful family environment are important risk factors for the OBD. Protective factors in parents, such as so ...

Article GUID: 39066987


Poor inhibition of personally-relevant facial expressions of sadness and anger predicts an elevated cortisol response following awakening six months later.

Author(s): Wong SF, Trespalacios F, Ellenbogen MA

Int J Psychophysiol. 2020 Feb 11;: Authors: Wong SF, Trespalacios F, Ellenbogen MA

Article GUID: 32057777


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