Author(s): Bietar K; Chu S; Mandl G; Zhang E; Chabaytah N; Sabelli R; Capobianco JA; Stochaj U;

Lanthanide-doped upconverting nanoparticles (UCNPs) are ideal candidates for use in biomedicine. The interaction of nanomaterials with biological systems determines whether they are suitable for use in living cells. In-depth knowledge of the nano-bio interactions is therefore a pre-requisite for the development of biomedical applications. The current stud ...

Article GUID: 38495986

Author(s): Mandl GA; Vettier F; Tessitore G; Maurizio SL; Bietar K; Stochaj U; Capobianco JA;

Glioblastoma multiforme is an aggressive type of brain cancer with high recurrence rates due to the presence of radioresistant cells remaining after tumor resection. Here, we report the development of an X-ray-mediated photodynamic therapy (X-PDT) system using NaLuF4:25% Pr3+ radioluminescent nanoparticles in conjunction with protoporphyrin IX (PPIX), an ...

Article GUID: 37267436

Author(s): Samhadaneh DM; Mandl GA; Han Z; Mahjoob M; Weber SC; Tuznik M; Rudko DA; Capobianco JA; Stochaj U;

Because of their unique physicochemical properties, lanthanide-doped upconverting nanoparticles (Ln-UCNPs) have exceptional potential for biological applications. However, the use in biological systems is hampered by the limited understanding of their bionano interactions. Our multidisciplinary s ...

Article GUID: 35025434