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Gold Nano-Bio-Interaction to Modulate Mechanobiological Responses for Cancer Therapy Applications

Author(s): Sohrabi Kashani A; Larocque K; Piekny A; Packirisamy M;

In the present study, we investigate the mechanobiological responses of human lung cancer that may occur through their interactions with two different types of gold nanoparticles: nanostars and nanospheres. Hyperspectral images of nanoparticle-treated cells revealed different spatial distributions of nanoparticles in cells depending on their morphology, w ...

Article GUID: 35839330


Cancer-Nano-Interaction: From Cellular Uptake to Mechanobiological Responses

Author(s): Sohrabi Kashani A; Packirisamy M;

With the advancement of nanotechnology, the nano-bio-interaction field has emerged. It is essential to enhance our understanding of nano-bio-interaction in different aspects to design nanomedicines and improve their efficacy for therapeutic and diagnostic applications. Many researchers have extensively studied the toxicological responses of cancer cells t ...

Article GUID: 34502495


Using intracellular plasmonics to characterize nanomorphology in human cells.

Author(s): Sohrabi Kashani A, Piekny A, Packirisamy M

Determining the characteristics and localization of nanoparticles inside cells is crucial for nanomedicine design for cancer therapy. Hyperspectral imaging is a fast, straightforward, reliable, and accurate method to study the interactions of nanoparticles and intracellular components. With a hyperspectral image, we could collect spectral information cons ...

Article GUID: 33365137


Efficient Low Shear Flow-based Trapping of Biological Entities.

Author(s): Sohrabi Kashani A, Packirisamy M

Sci Rep. 2019 Apr 02;9(1):5511 Authors: Sohrabi Kashani A, Packirisamy M

Article GUID: 30940862


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