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pH-Responsive Degradable Electro-Spun Nanofibers Crosslinked via Boronic Ester Chemistry for Smart Wound Dressings

Author(s): Casillas-Popova SN; Lokuge ND; Andrade-Gagnon B; Chowdhury FR; Skinner CD; Findlay BL; Oh JK;

Recent advances in the treatment of chronic wounds have focused on the development of effective strategies for cutting-edge wound dressings based on nanostructured materials, particularly biocompatible poly(vinyl alcohol) (PVA)-based electro-spun (e-spun) nanofibers. However, PVA nanofibers need ...

Article GUID: 38989606


A threshold LC-MS/MS method for 92 analytes in oral fluid collected with the Quantisal® device

Author(s): Desharnais B; Lajoie MJ; Laquerre J; Mireault P; Skinner CD;

A study of impaired driving rates in the province of Québec is currently planned following the legalization of recreational cannabis in Canada. Oral fluid (OF) samples are to be collected with a Quantisal® device and sent to the laboratory for analysis. In order to prepare for this project, a qualitative decision point analysis method monitoring for the p ...

Article GUID: 33035929


The Key Role of Intrinsic Lifetime Dynamics from Upconverting Nanosystems in Multiemission Particle Velocimetry

Author(s): Tessitore G; Maurizio SL; Sabri T; Skinner CD; Capobianco JA;

Evaluation of particle dynamics at the nano- and microscale poses a challenge to the development of novel velocimetry techniques. Established optical methods implement external or internal calibrations of the emission profiles by varying the particle velocity and are limited to specific experimental conditions. The proposed multiemission particle velocime ...

Article GUID: 32924221


Qualitative threshold method validation and uncertainty evaluation: A theoretical framework and application to a 40 analytes liquid chromatography-tandem mass spectrometry method

Author(s): Camirand Lemyre F; Desharnais B; Laquerre J; Morel MA; Côté C; Mireault P; Skinner CD;

Qualitative methods hold an important place in drug testing, filling central needs in screening and analyses, among others, linked to per se legislation. Nevertheless, the bioanalytical method validation guidelines do not discuss this type of method or describe method validation procedures ill-adapted to qualitative methods. The output of qualitative meth ...

Article GUID: 32476284


Capillary electrochromatography of peptides and proteins.

Author(s): Bandilla D, Skinner CD

J Chromatogr A. 2004 Jul 30;1044(1-2):113-29 Authors: Bandilla D, Skinner CD

Article GUID: 15354432


Design and optimization of porous polymer enzymatic digestors for proteomics.

Author(s): Lin W, Skinner CD

J Sep Sci. 2009 Aug;32(15-16):2642-52 Authors: Lin W, Skinner CD

Article GUID: 19575382


Increased oxidative modifications of amniotic fluid albumin in pregnancies associated with gestational diabetes mellitus.

Author(s): Boisvert MR, Koski KG, Skinner CD

Anal Chem. 2010 Feb 01;82(3):1133-7 Authors: Boisvert MR, Koski KG, Skinner CD

Article GUID: 20063865


A case of fatal idiosyncratic reaction to the designer drug 3,4-methylenedioxypyrovalerone (MDPV) and review of the literature.

Author(s): Desharnais B, Dazé Y, Huppertz LM, Mireault P, Skinner CD

Forensic Sci Med Pathol. 2017 Sep;13(3):350-354 Authors: Desharnais B, Dazé Y, Huppertz LM, Mireault P, Skinner CD

Article GUID: 28668987


A Tool for Automatic Correction of Endogenous Concentrations: Application to BHB Analysis by LC-MS-MS and GC-MS

Author(s): Desharnais B; Lajoie MJ; Laquerre J; Savard S; Mireault P; Skinner CD;

Several substances relevant for forensic toxicology purposes have an endogenous presence in biological matrices: beta-hydroxybutyric acid (BHB), gamma-hydroxybutyric acid (GHB), steroids and human insulin, to name only a few. The presence of significant amounts of these endogenous substances in the biological matrix used to prepare calibration standards a ...

Article GUID: 31141151


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