1 School of Health and Exercise Sciences, University of British Columbia Okanagan, Kelowna, BC V1V 1V7, Canada.
2 Healthy Active Living and Obesity Research Group, Children's Hospital of Eastern Ontario Research Institute, Ottawa, ON K1H 8L1, Canada.
3 School of Kinesiology and Health Studies, Queen's University, Kingston, ON K7L 3N6, Canada.
4 Department of Pediatrics, University of Ottawa, Ottawa, ON K1N 6N5, Canada.
5 School of Human Kinetics, Faculty of Health Sciences, University of Ottawa, Ottawa, ON K1N 6N5, Canada.
6 School of Psychology, University of Ottawa, Ottawa, ON K1N 6N5, Canada.
7 Clinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa, ON K1Y 4E9, Canada.
8 Departments of Medicine, Cardiac Sciences and Community Health Sciences, Cumming School of Medicine, University of Calgary, Calgary, AB T2N 4N1, Canada.
9 Department of Community Health & Epidemiology, Dalhousie University, Halifax, NS B3H 4R2, Canada.
10 Centre for Healthy Active Living, Children's Hospital of Eastern Ontario Research Institute, Ottawa, ON K1H 8L1, Canada.
11 Department of Health, Kinesiology & Applied Physiology, Concordia University, Montreal, QC H4B 1R6, Canada.
12 Institut du Savoir Montfort, Ottawa, ON K1K 0T2, Canada.

Interindividual variability and individual responses to exercise training in adolescents with obesity.

Appl Physiol Nutr Metab. 2019 May 23;:

Authors: Walsh JJ, Bonafiglia JT, Goldfield GS, Sigal RJ, Kenny GP, Doucette S, Hadjiyannakis S, Alberga AS, Prud'homme D, Gurd BJ

Abstract

This study investigated the impact of exercise training on interindividual variability and response rates in body composition and cardiometabolic outcomes in adolescents with obesity. Postpubertal males and females (n=143) were randomly assigned to six-months of a diet-only Control or Aerobic, Resistance, or Combined exercise training. Body composition indices were percentages of body fat mass (%BFM) and lean body mass (%LBM), and waist circumference (WC). Biomarkers of cardiometabolic health were systolic blood pressure (SBP) and plasma fasting glucose, triglycerides, and high-density lipoprotein cholesterol. Interindividual variability was examined by comparing the standard deviation of individual responses (SDIR) to a smallest robust change (SRC). The typical error of measurement was used to classify responses. SDIR exceeded the SRC for %BFM in all exercise groups (SRC=1.04%; Aerobic SDIR=1.50%; Resistance SDIR=1.22%; Combined SDIR=2.29%), %LBM (SRC=1.38%; SDIR=3.2%,) and SBP (SRC=2.06 mmHg; SDIR=4.92 mmHg) in the Resistance group, and WC (SRC=2.33 cm; SDIR=4.09 cm) and fasting glucose (SRC=0.08 mmol/L; SDIR=0.28 mmol/L) in the Combined group. However, half of the reported variables (11/21) did not have a positive SDIR. Importantly, adverse response rates were significantly lower in all three exercise groups than control for body composition. Although exercise had a small influence on interindividual variability for indices of body composition, the rate of adverse responses did not increase for any outcome. -Interindividual variability and individual responses to exercise training have not been investigated in adolescents with obesity. -Six-months of exercise training does not increase interindividual variability in adolescents with obesity. -Exercise created a positive, uniform shift in responses.

PMID: 31121100 [PubMed - as supplied by publisher]