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Hypothalamic-pituitary-adrenal axis function in the offspring of parents with bipolar disorder and the impact of the family environment: A pilot study of the Reducing Unwanted Stress in the Home (RUSH) prevention program

Author(s): Ping EY; Herriot H; Iacono V; Serravalle L; Ellenbogen MA;

Background: The home environment of offspring of parents with bipolar disorder (OBD) has been characterized by high levels of stress and disorganization, which may impact development of the hypothalamic-pituitary-adrenal (HPA) axis and their subsequent risk for affective disorders. The present study examined the effects of a family-based preventative inte ...

Article GUID: 39357242


Hypothalamic-pituitary-adrenal axis functioning in offspring of parents with a major affective disorder: a meta-analytic review

Author(s): Serravalle L; Trespalacios F; Ellenbogen MA;

Because the offspring of parents with an affective disorder (OAD) are at high risk for developing mental disorders, and persons with an affective disorder (AD) show dysfunctional hypothalamic-pituitary-adrenal (HPA) axis activity, changes in HPA functioning in OAD might be an etiological risk factor that precedes the development of ADs. The primary aim of ...

Article GUID: 39207496


The perceived social support of parents having bipolar disorder impacts their children's mental health: a 10-year longitudinal study

Author(s): Trespalacios F; Boyle A; Serravalle L; Hodgins S; Ellenbogen MA;

Background: The offspring of parents with bipolar disorder (OBD) are at higher risk of developing psychopathology than the offspring of parents with no affective disorder (control). In addition to genetic predisposition, childhood adversity and a stressful family environment are important risk factors for the OBD. Protective factors in parents, such as so ...

Article GUID: 39066987


The effects of intranasal oxytocin on the efficacy of psychotherapy for major depressive disorder: a pilot randomized controlled trial

Author(s): Ellenbogen MA; Cardoso C; Serravalle L; Vadaga K; Joober R;

Background: Although both pharmacotherapy and psychological treatments are considered to be efficacious in the treatment of major depressive disorder (MDD), one third of patients do not respond to treatment and many experience residual symptoms post-treatment. In this double-blind placebo-controlled randomized control trial (RCT), we assessed whether intr ...

Article GUID: 38445382


Reduced parenting stress following a prevention program decreases internalizing and externalizing symptoms in the offspring of parents with bipolar disorder

Author(s): Resendes T; Serravalle L; Iacono V; Ellenbogen MA;

Background: Offspring of parents with bipolar disorder (OBD) are at risk for developing mental disorders, and the literature suggests that parenting stress may represent an important risk factor linking parental psychopathology to offspring psychopathology. We aimed to investigate whether improvements in parenting stress mediated the relationship between ...

Article GUID: 36849568


Correction to: Improved Parent-Child Interactions Predict Reduced Internalizing Symptoms Among the Offspring of Parents with Bipolar Disorder Undergoing a Prevention Program: A Proof‑of‑Concept Study

Author(s): Serravalle L; Iacono V; Wilson AL; Orlando MA; Tsekova V; Ellenbogen MA;

No abstract available

Article GUID: 33835373


Improved Parent-Child Interactions Predict Reduced Internalizing Symptoms Among the Offspring of Parents with Bipolar Disorder Undergoing a Prevention Program: A Proof-of-Concept Study

Author(s): Serravalle L; Iacono V; Wilson AL; Orlando MA; Tsekova V; Ellenbogen MA;

The offspring of parents with bipolar disorder (OBD) exhibit elevated rates of psychopathology. However, preventative interventions are lacking. Using a quasi-experimental design with an assessment-only control group, we examined if a 12-week program (entitled Reducing Unwanted Stress in the Home, RUSH) decreases internalizing and externalizing symptoms i ...

Article GUID: 33544277


Predicting Interpersonal Outcomes From Information Processing Tasks Using Personally Relevant and Generic Stimuli: A Methodology Study

Author(s): Serravalle L; Tsekova V; Ellenbogen MA;

Despite evidence of differential processing of personally relevant stimuli (PR), most studies investigating attentional biases in processing emotional content use generic stimuli. We sought to examine differences in the processing of PR, relative to generic, stimuli across information processing tasks and to validate their use in predicting concurrent int ...

Article GUID: 33071861


A comprehensive assessment of personality traits and psychosocial functioning in parents with bipolar disorder and their intimate partners

Author(s): Serravalle L; Iacono V; Hodgins S; Ellenbogen MA;

Background: Individuals with bipolar disorder (BD) often possess maladaptive traits and present with various difficulties in psychosocial functioning. However, little is known about the intimate partners of adults with bipolar disorder (BD) and how mental illnesses other than BD within couples may further complicate the picture. Such knowledge is needed t ...

Article GUID: 32037491


Stress-induced negative mood moderates the relation between oxytocin administration and trust: evidence for the tend-and-befriend response to stress?

Author(s): Cardoso C, Ellenbogen MA, Serravalle L, Linnen AM

Psychoneuroendocrinology. 2013 Nov;38(11):2800-4 Authors: Cardoso C, Ellenbogen MA, Serravalle L, Linnen AM

Article GUID: 23768973


Oxytocin and social context moderate social support seeking in women during negative memory recall.

Author(s): Cardoso C, Valkanas H, Serravalle L, Ellenbogen MA

Psychoneuroendocrinology. 2016 08;70:63-9 Authors: Cardoso C, Valkanas H, Serravalle L, Ellenbogen MA

Article GUID: 27164224


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