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Learning processes in relapse to alcohol use: lessons from animal models

Author(s): Valyear MD; LeCocq MR; Brown A; Villaruel FR; Segal D; Chaudhri N;

Rationale: Alcohol use is reliably preceded by discrete and contextual stimuli which, through diverse learning processes, acquire the capacity to promote alcohol use and relapse to alcohol use. Objective: We review contemporary extinction, renewal, reinstatement, occasion setting, and sex differences research within a conditioning framework of relapse to ...

Article GUID: 36264342


Supplementary dataset of context-dependent conditioned responding to an alcohol-predictive cue in female and male rats

Author(s): Segal D; Valyear MD; Chaudhri N;

This supplementary dataset is supportive of the research article entitled 'The role of context on responding to an alcohol-predictive cue in female and male rats' [1]. This article describes the raw data pertaining to the behaviour of male and female rats during intermittent to ethanol and Pavlovian conditioning training and testing procedures. Sp ...

Article GUID: 35330738


The role of context on responding to an alcohol-predictive cue in female and male rats

Author(s): Segal D; Valyear MD; Chaudhri N;

In male rats, physical contexts that are associated with alcohol can amplify responding to a discrete, alcohol-predictive conditioned stimulus (CS), and amplify prime-induced reinstatement. Here, we examined these effects as a function of biological sex. Male and female Long-Evans rats were acclimated to drinking ethanol (15% v/v) in their home cages. Nex ...

Article GUID: 34742865


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