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Droplet digital microfluidic system for screening filamentous fungi based on enzymatic activity

Author(s): Samlali K; Alves CL; Jezernik M; Shih SCC;

Fungal cell-wall-degrading enzymes have great utility in the agricultural and food industries. These cell-wall-degrading enzymes are known to have functions that can help defend against pathogenic organisms. The existing methods used to discover these enzymes are not well adapted to fungi culture and morphology, which prevents the proper evaluation of the ...

Article GUID: 36438986


Community-led risk analysis of direct-to-consumer whole-genome sequencing

Author(s): Samlali K; Thornbury M; Venter A;

Direct-to-consumer (DTC) genetic testing is cheaper and more accessible than ever before. What is generally hidden from the consumer is the intention to combine, reuse, and resell this genetic information as powerful datasets. This financial gain is creating a competitive DTC market, reducing the price of whole genome sequencing (WGS) down to USD 299. Ent ...

Article GUID: 35939839


Digital Microfluidics Chips for the Execution and Real-Time Monitoring of Multiple Ribozymatic Cleavage Reactions

Author(s): Davis AN; Samlali K; Kapadia JB; Perreault J; Shih SCC; Kharma N;

In this paper, we describe the design and performance of two digital microfluidics (DMF) chips capable of executing multiple ribozymatic reactions, with proper controls, in response to short single-stranded DNA inducers. Since the fluorescence output of a reaction is measurable directly from the chip, without the need for gel electrophoresis, a complete e ...

Article GUID: 34514224


One Cell, One Drop, One Click: Hybrid Microfluidics for Mammalian Single Cell Isolation.

Author(s): Samlali K, Ahmadi F, Quach ABV, Soffer G, Shih SCC

Small. 2020 Jul 23;:e2002400 Authors: Samlali K, Ahmadi F, Quach ABV, Soffer G, Shih SCC

Article GUID: 32705796


An integrated droplet-digital microfluidic system for on-demand droplet creation, mixing, incubation, and sorting.

Author(s): Ahmadi F, Samlali K, Vo PQN, Shih SCC

Lab Chip. 2019 01 29;19(3):524-535 Authors: Ahmadi F, Samlali K, Vo PQN, Shih SCC

Article GUID: 30633267


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