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Impact of a national dementia research consortium: The Canadian Consortium on Neurodegeneration in Aging (CCNA)

Author(s): Chertkow H; Phillips N; Rockwood K; Anderson N; Andrew MK; Bartha R; Beaudoin C; Bélanger N; Bellec P; Belleville S; Bergman H; Best S; Bethell J; Bherer L; Black S; Borrie M; Camicioli R; Carrier J; Cashman N; Chan S; Crowshoe L; Cuello ...

The Canadian Consortium on Neurodegeneration in Aging (CCNA) was created by the Canadian federal government through its health research funding agency, the Canadian Institutes for Health Research (CIHR), in 2014, as a response to the G7 initiative to fight dementia. Two five-year funding cycles ( ...

Article GUID: 39636028


MuscleMap: An Open-Source, Community-Supported Consortium for Whole-Body Quantitative MRI of Muscle

Author(s): McKay MJ; Weber KA; Wesselink EO; Smith ZA; Abbott R; Anderson DB; Ashton-James CE; Atyeo J; Beach AJ; Burns J; Clarke S; Collins NJ; Coppieters MW; Cornwall J; Crawford RJ; De Martino E; Dunn AG; Eyles JP; Feng HJ; Fortin M; Franettovic ...

Disorders affecting the neurological and musculoskeletal systems represent international health priorities. A significant impediment to progress in trials of new therapies is the absence of responsive, objective, and valid outcome measures sensitive to early disease changes. A key finding in indi ...

Article GUID: 39590726


The hockey fans in training intervention for men with overweight or obesity: a pragmatic cluster randomised trial

Author(s): Petrella RJ; Gill DP; Boa Sorte Silva NC; Riggin B; Blunt WM; Kfrerer M; Majoni M; Marsh J; Irwin JD; Stranges S; Zwarenstein M; Zou G;

Background: Obesity disproportionately impacts men's health yet fewer men engage in preventive healthcare. We examined the effectiveness of Hockey Fans in Training (Hockey FIT), a gender-sensitised lifestyle intervention that engages men with overweight/obesity through their passion as fans o ...

Article GUID: 39568632


Geological Net Zero and the need for disaggregated accounting for carbon sinks

Author(s): Allen MR; Frame DJ; Friedlingstein P; Gillett NP; Grassi G; Gregory JM; Hare W; House J; Huntingford C; Jenkins S; Jones CD; Knutti R; Lowe JA; Matthews HD; Meinshausen M; Meinshausen N; Peters GP; Plattner GK; Raper S; Rogelj J; Stott P ...

Achieving net zero global emissions of carbon dioxide (CO2), with declining emissions of other greenhouse gases, is widely expected to halt global warming. CO2 emissions will continue to drive warming until fully balanced by active anthropogenic CO2 removals. For practical reasons, however, many ...

Article GUID: 39557072


Development of SNP Panels from Low-Coverage Whole Genome Sequencing (lcWGS) to Support Indigenous Fisheries for Three Salmonid Species in Northern Canada

Author(s): Beemelmanns A; Bouchard R; Michaelides S; Normandeau E; Jeon HB; Chamlian B; Babin C; Hénault P; Perrot O; Harris LN; Zhu X; Fraser D; Bernatchez L; Moore JS;

Single nucleotide polymorphism (SNP) panels are powerful tools for assessing the genetic population structure and dispersal of fishes and can enhance management practices for commercial, recreational and subsistence mixed-stock fisheries. Arctic Char (Salvelinus alpinus), Brook Trout (Salvelinus ...

Article GUID: 39552382


Exploring the Qualitative Experiences of Administering and Participating in Remote Research via Telephone Using the Montreal Cognitive Assessment-Blind: Cross-Sectional Study of Older Adults

Author(s): Dumassais S; Grewal KS; Aubin G; O' Connell M; Phillips NA; Wittich W;

Background: The COVID-19 pandemic caused a drastic shift in the practice of research and clinical services. It has been noted that cognition measured via in-person versus remote methods differ substantially, and it is possible that subjective and experiential differences exist between modalities. Objective: The aim of the study is to explore the percepti ...

Article GUID: 39546346


Monitoring pilot trainees' cognitive control under a simulator-based training process with EEG microstate analysis

Author(s): Zhao M; Jia W; Jennings S; Law A; Bourgon A; Su C; Larose MH; Grenier H; Bowness D; Zeng Y;

The objective of pilot training is to equip trainees with the knowledge, judgment, and skills to maintain control of an aircraft and respond to critical flight tasks. The present research aims to investigate changes in trainees' cognitive control levels during a pilot training process while t ...

Article GUID: 39428425


Perceptions of carbon dioxide emission reductions and future warming among climate experts

Author(s): Wynes S; Davis SJ; Dickau M; Ly S; Maibach E; Rogelj J; Zickfeld K; Matthews HD;

The Intergovernmental Panel on Climate Change (IPCC) employs emission scenarios to explore a range of future climate outcomes but refrains from assigning probabilities to individual scenarios. However, IPCC authors have their own views on the likelihood of different climate outcomes, which are valuable to understand because authors possess both expert ins ...

Article GUID: 39280638


Comparative genomic analysis of thermophilic fungi reveals convergent evolutionary adaptations and gene losses

Author(s): Steindorff AS; Aguilar-Pontes MV; Robinson AJ; Andreopoulos B; LaButti K; Kuo A; Mondo S; Riley R; Otillar R; Haridas S; Lipzen A; Grimwood J; Schmutz J; Clum A; Reid ID; Moisan MC; Butler G; Nguyen TTM; Dewar K; Conant G; Drula E; Henri ...

Thermophily is a trait scattered across the fungal tree of life, with its highest prevalence within three fungal families (Chaetomiaceae, Thermoascaceae, and Trichocomaceae), as well as some members of the phylum Mucoromycota. We examined 37 thermophilic and thermotolerant species and 42 mesophil ...

Article GUID: 39266695


Show me the evidence to guide nutrition practice: Scoping review of macronutrient dietary treatments after metabolic and bariatric surgery

Author(s): Parrott JM; Benson-Davies S; O' Kane M; Sherf-Dagan S; Ben-Porat T; Arcone VM; Faria SL; Parrott JS;

Background: Clinical practice recommendations for macronutrient intake in Metabolic and Bariatric Surgery (MBS) are insufficiently grounded in the research, possibly due to a paucity of research in key areas necessary to support macronutrient recommendations. An initial scoping r ...

Article GUID: 39262138


The perceived social support of parents having bipolar disorder impacts their children's mental health: a 10-year longitudinal study

Author(s): Trespalacios F; Boyle A; Serravalle L; Hodgins S; Ellenbogen MA;

Background: The offspring of parents with bipolar disorder (OBD) are at higher risk of developing psychopathology than the offspring of parents with no affective disorder (control). In addition to genetic predisposition, childhood adversity and a stressful family environment are important risk factors for the OBD. Protective factors in parents, such as so ...

Article GUID: 39066987


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