Author(s): Monnin C; Ramrup P; Daigle-Young C; Vuckovic D;

Rationale: Mobile-phase additives in liquid chromatography/mass spectrometry (LC/MS) are used to improve peak shape, analyte ionization efficiency and method coverage. Both basic and acidic mobile phases have been used successfully for negative electrospray ionization (ESI), but very few systematic investigations exist to date to justify the choice of mob ...

Article GUID: 29105990