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Acute ethanol disrupts conditioned inhibition in the male rat

Author(s): Germé K; Pfaus JG;

Rationale: Alcohol can disrupt conditioned sexual inhibition (CSI) established by first-order conditioning in male rats. CSI can also be induced using second-order conditioning, during which male rats are trained to associate a neutral odor with a nonreceptive female. As a result, when given access to two receptive females (one scented and one unscented) ...

Article GUID: 38822097


Effects of cabergoline and dimethylcabergoline on the sexual behavior of male rats

Author(s): Pfaus JG; Antonie RA; Dosa PI; Kim SW;

Rationale: Cabergoline (CAB) is an ergot derivative typically prescribed for the treatment of hyperprolactinemia. It suppresses the release of prolactin through agonist actions on dopamine (DA) D2 receptors; however, it possesses binding affinity for other DA and 5-HT receptors. Side effects that exacerbate valvular heart disease can occur with high doses ...

Article GUID: 37968530


Reciprocal effects of single or repeated exposure to methylphenidate or sex in adult male rats

Author(s): Pallikaras V; Mac Cionnaith CE; Rosales VCF; Arvanitogiannis A; Pfaus JG;

Rationale: Exposure to rewards can alter behavioral reactivity to them. For example, stimulants sensitize locomotor activation, whereas sexual experience sensitizes copulatory behaviors. Moreover, rewards can cross-sensitize one another. Although stimulants are known to cross-sensitize locomotor effects, the evidence for cross-sensitization between stimul ...

Article GUID: 36544054


Acute caffeine reverses the disruptive effects of chronic fluoxetine on the sexual behavior of female and male rats.

Author(s): González Cautela BV; Quintana GR; Akerman J; Pfaus JG;

RATIONALE: Sexual side effects of chronic treatment with selective serotonin reuptake inhibitors (SSRIs) in humans include anorgasmia and loss of sexual desire and/or arousal which interferes with treatment compliance. There are few options at present to reduce these effects. Because orgasm and desire are mediated in part by activation of sympathetic arou ...

Article GUID: 33242109


Appetitive olfactory conditioning in the neonatal male rat facilitates subsequent sexual partner preference.

Author(s): Ménard S, Gelez H, Jacubovitch M, Coria-Avila GA, Pfaus JG

Pairing a neutral odor with a male rat's initial sexual experiences to ejaculation produces a subsequent conditioned ejaculatory preference (CEP) in which males ejaculate preferentially with receptive females that bear the odor relative to unscented receptive females. In 1986, Fillion and Blass reported that neonatal male rats exposed to a neutral lem ...

Article GUID: 32919208


Conditioning of Sexual Interests and Paraphilias in Humans Is Difficult to See, Virtually Impossible to Test, and Probably Exactly How It Happens: A Comment on Hsu and Bailey (2020).

Author(s): Pfaus JG, Quintana GR, Mac Cionnaith CE, Gerson CA, Dubé S, Coria-Avila GA

Arch Sex Behav. 2020 May 27;: Authors: Pfaus JG, Quintana GR, Mac Cionnaith CE, Gerson CA, Dubé S, Coria-Avila GA PMID: 32462414 [PubMed - as supplied by publisher]

Article GUID: 32462414


The non-aromatizable androgen dihydrotestosterone (DHT) facilitates sexual behavior in ovariectomized female rats primed with estradiol.

Author(s): Maseroli E, Santangelo A, Lara-Fontes B, Quintana GR, Mac Cionnaith CE, Casarrubea M, Ricca V, Maggi M, Vignozzi L, Pfaus JG

Psychoneuroendocrinology. 2020 Feb 07;115:104606 Authors: Maseroli E, Santangelo A, Lara-Fontes B, Quintana GR, Mac Cionnaith CE, Casarrubea M, Ricca V, Maggi M, Vignozzi L, Pfaus JG

Article GUID: 32087523


Correction to: Differential disruption of conditioned ejaculatory preference in the male rat based on different sensory modalities by micro-infusions of naloxone to the medial preoptic area or ventral tegmental area.

Author(s): Quintana GR, Birrel M, Marceau S, Kalantari N, Bowden J, Bachoura Y, Borduas E, Lemay V, Payne JW, Cionnaith CM, Pfaus JG

Psychopharmacology (Berl). 2020 Jan 09;: Authors: Quintana GR, Birrel M, Marceau S, Kalantari N, Bowden J, Bachoura Y, Borduas E, Lemay V, Payne JW, Cionnaith CM, Pfaus JG

Article GUID: 31919562


Behavior is the ultimate arbiter: An alternative explanation for the inhibitory effect of fluoxetine on the ovulatory homolog model of orgasm in rabbits.

Author(s): Quintana GR, Mac Cionnaith CE, Pfaus JG

Proc Natl Acad Sci U S A. 2019 Dec 03;: Authors: Quintana GR, Mac Cionnaith CE, Pfaus JG PMID: 31796602 [PubMed - as supplied by publisher]

Article GUID: 31796602


Fos expression is increased in oxytocin neurons of female rats with a sexually conditioned mate preference for an individual male rat.

Author(s): Mac Cionnaith CE, Lemay A, Gomez-Perales EL, Robert G, Cernik R, Brake W, Pfaus JG

Horm Behav. 2019 Oct 21;:104612 Authors: Mac Cionnaith CE, Lemay A, Gomez-Perales EL, Robert G, Cernik R, Brake W, Pfaus JG

Article GUID: 31647923


Aromatization Is Not Required for the Facilitation of Appetitive Sexual Behaviors in Ovariectomized Rats Treated With Estradiol and Testosterone.

Author(s): Jones SL, Rosenbaum S, Gardner Gregory J, Pfaus JG

Front Neurosci. 2019;13:798 Authors: Jones SL, Rosenbaum S, Gardner Gregory J, Pfaus JG

Article GUID: 31447629


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