Author(s): Yazdanpanah Moghadam E; Sonenberg N; Packirisamy M;

Microglial cells, or brain immune cells, are highly dynamic and continuously migrate in pathophysiological conditions. Their adhesion, as a physical characteristic, plays a key role in migration. In this study, we presented a microfluidic chip combination of two assays: a microglial BV2 adhesion assay and a wound-healing migration assay. The chip could cr ...

Article GUID: 39203655

Author(s): Derayatifar M; Habibi M; Bhat R; Packirisamy M;

Direct sound printing (DSP), an alternative additive manufacturing process driven by sonochemical polymerization, has traditionally been confined to a single acoustic focal region, resulting in a voxel-by-voxel printing approach. To overcome this limitation, we introduce holographic direct sound printing (HDSP), where acoustic holograms, storing cross-sec ...

Article GUID: 39107289

Author(s): Yazdanpanah Moghadam E; Sonenberg N; Packirisamy M;

Microglia cells, as the resident immune cells of the central nervous system (CNS), are highly motile and migratory in development and pathophysiological conditions. During their migration, microglia cells interact with their surroundings based on the various physical and chemical properties in the brain. Herein, a microfluidic wound-healing chip is develo ...

Article GUID: 36832056

Author(s): Pou KRJ; Raghavan V; Packirisamy M;

The increasing trend in ensuring safe and quality foods necessitates the monitoring of food products throughout the food supply chain. Food packaging is an indispensable process as it provides various functions such as containment, protection, convenience, and communication. The development of innovative packaging systems is required to ensure foods are m ...

Article GUID: 36192908

Author(s): Sohrabi Kashani A; Larocque K; Piekny A; Packirisamy M;

In the present study, we investigate the mechanobiological responses of human lung cancer that may occur through their interactions with two different types of gold nanoparticles: nanostars and nanospheres. Hyperspectral images of nanoparticle-treated cells revealed different spatial distributions of nanoparticles in cells depending on their morphology, w ...

Article GUID: 35839330

Author(s): Raju D; Bathini S; Badilescu S; Ghosh A; Packirisamy M;

Extracellular vesicles (EVs) are a group of communication organelles enclosed by a phospholipid bilayer, secreted by all types of cells. The size of these vesicles ranges from 30 to 1000 nm, and they contain a myriad of compounds such as RNA, DNA, proteins, and lipids from their origin cells, offering a good source of biomarkers. Exosomes (30 to 100 nm) a ...

Article GUID: 35630197

Author(s): Habibi M; Foroughi S; Karamzadeh V; Packirisamy M;

Photo- and thermo-activated reactions are dominant in Additive Manufacturing (AM) processes for polymerization or melting/deposition of polymers. However, ultrasound activated sonochemical reactions present a unique way to generate hotspots in cavitation bubbles with extraordinary high temperature and pressure along with high heating and cooling rates whi ...

Article GUID: 35387993

Author(s): Kuruvinashetti K; Packirisamy M;

Microphotosynthetic power cells (µPSCs) generate power through the exploitation of living photosynthetic microorganisms by harvesting sunlight. The thermodynamic limitations of this process restrict the power output of a single µPSC. Herein, we demonstrate µPSCs in four different array configurations to enhance power output from these power cells. To this ...

Article GUID: 35359612

Author(s): Kuruvinashetti K; Rahimi S; Pakkiriswami S; Packirisamy M;

Ongoing technological advancements continually increase the demand for energy. Among various types of energy harvesting systems, biologically based systems have been an area of increasing interest for the past couple of decades. Such systems provide clean, safe power solutions, mainly for low- and ultra-low-power applications. The microphotosynthetic powe ...

Article GUID: 34898042

Author(s): Bathini S; Pakkiriswami S; Ouellette RJ; Ghosh A; Packirisamy M;

Extracellular vesicles (EVs) are the cell-derived vesicles which play a critical role in cell-to-cell communication, and disease progression. These vesicles contain a myriad of substances like RNA, DNA, proteins, and lipids from their origin cells, offering a good source of biomarkers. The existing methods for the isolation of EVs are time-consuming, lack ...

Article GUID: 34517262

Author(s): Sohrabi Kashani A; Packirisamy M;

With the advancement of nanotechnology, the nano-bio-interaction field has emerged. It is essential to enhance our understanding of nano-bio-interaction in different aspects to design nanomedicines and improve their efficacy for therapeutic and diagnostic applications. Many researchers have extensively studied the toxicological responses of cancer cells t ...

Article GUID: 34502495