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Data-driven methods distort optimal cutoffs and accuracy estimates of depression screening tools: a simulation study using individual participant data

Author(s): Bhandari PM; Levis B; Neupane D; Patten SB; Shrier I; Thombs BD; Benedetti A;

Objective: To evaluate, across multiple sample sizes, the degree that data-driven methods result in (1) optimal cutoffs different from population optimal cutoff and (2) bias in accuracy estimates. Study design and setting: A total of 1,000 samples of sample size 100, 200, 500 and 1,000 each were randomly drawn to simulate studies of different sample size ...

Article GUID: 33838273


Overestimation of Postpartum Depression Prevalence Based on a 5-item Version of the EPDS: Systematic Review and Individual Participant Data Meta-analysis

Author(s): Thombs BD; Levis B; Lyubenova A; Neupane D; Negeri Z; Wu Y; Sun Y; He C; Krishnan A; Vigod SN; Bhandari PM; Imran M; Rice DB; Azar M; Chiovitti MJ; Saadat N; Riehm KE; Boruff JT; Cuijpers P; Gilbody S; Ioannidis JPA; Kloda LA; Patten SB; ...

Objective: The Maternal Mental Health in Canada, 2018/2019, survey reported that 18% of 7,085 mothers who recently gave birth reported "feelings consistent with postpartum depression" based on scores =7 on a 5-item version of the Edinburgh Postpartum Depression Scale (EPDS-5). The EPDS-5 was desi ...

Article GUID: 33104415


Depression prevalence based on the Edinburgh Postnatal Depression Scale compared to Structured Clinical Interview for DSM DIsorders classification: Systematic review and individual participant data meta-analysis

Author(s): Lyubenova A; Neupane D; Levis B; Wu Y; Sun Y; He C; Krishnan A; Bhandari PM; Negeri Z; Imran M; Rice DB; Azar M; Chiovitti MJ; Saadat N; Riehm KE; Boruff JT; Ioannidis JPA; Cuijpers P; Gilbody S; Kloda LA; Patten SB; Shrier I; Ziegelstei ...

Objectives: Estimates of depression prevalence in pregnancy and postpartum are based on the Edinburgh Postnatal Depression Scale (EPDS) more than on any other method. We aimed to determine if any EPDS cutoff can accurately and consistently estimate depression prevalence in individual studies. Me ...

Article GUID: 33089942


Protocol for a partially nested randomised controlled trial to evaluate the effectiveness of the scleroderma patient-centered intervention network COVID-19 home-isolation activities together (SPIN-CHAT) program to reduce anxiety among at-risk scleroderma patients.

Author(s): Thombs BD, Kwakkenbos L, Carrier ME, Bourgeault A, Tao L, Harb S, Gagarine M, Rice D, Bustamante L, Ellis K, Duchek D, Wu Y, Bhandari PM, Neupane D, Carboni-Jiménez A, Henry RS, Krishnan A, Sun Y, Levis B, He C, Turner KA, Benedetti A, C ...

J Psychosom Res. 2020 May 14;135:110132 Authors: Thombs BD, Kwakkenbos L, Carrier ME, Bourgeault A, Tao L, Harb S, Gagarine M, Rice D, Bustamante L, Ellis K, Duchek D, Wu Y, Bhandari PM, Neupane D, Carboni-Jiménez A, Henry RS, Krishnan A, Sun Y, Levis B, He C, Turner KA, Benedetti A, Culos- ...

Article GUID: 32521358


Patient Health Questionnaire-9 scores do not accurately estimate depression prevalence: individual participant data meta-analysis

Author(s): Levis B; Benedetti A; Ioannidis JPA; Sun Y; Negeri Z; He C; Wu Y; Krishnan A; Bhandari PM; Neupane D; Imran M; Rice DB; Riehm KE; Saadat N; Azar M; Boruff J; Cuijpers P; Gilbody S; Kloda LA; McMillan D; Patten SB; Shrier I; Ziegelstein R ...

Objectives: Depression symptom questionnaires are not for diagnostic classification. Patient Health Questionnaire-9 (PHQ-9) scores =10 are nonetheless often used to estimate depression prevalence. We compared PHQ-9 =10 prevalence to Structured Clinical Interview for Diagnostic and Statistical Man ...

Article GUID: 32105798


Probability of major depression diagnostic classification based on the SCID, CIDI and MINI diagnostic interviews controlling for Hospital Anxiety and Depression Scale - Depression subscale scores: An individual participant data meta-analysis of 73 primary studies

Author(s): Wu Y; Levis B; Sun Y; Krishnan A; He C; Riehm KE; Rice DB; Azar M; Yan XW; Neupane D; Bhandari PM; Imran M; Chiovitti MJ; Saadat N; Boruff JT; Cuijpers P; Gilbody S; McMillan D; Ioannidis JPA; Kloda LA; Patten SB; Shrier I; Ziegelstein R ...

Objective: Two previous individual participant data meta-analyses (IPDMAs) found that different diagnostic interviews classify different proportions of people as having major depression overall or by symptom levels. We compared the odds of major depression classification across diagnostic intervi ...

Article GUID: 31911325


Comparison of major depression diagnostic classification probability using the SCID, CIDI, and MINI diagnostic interviews among women in pregnancy or postpartum: An individual participant data meta-analysis

Author(s): Levis B; McMillan D; Sun Y; He C; Rice DB; Krishnan A; Wu Y; Azar M; Sanchez TA; Chiovitti MJ; Bhandari PM; Neupane D; Saadat N; Riehm KE; Imran M; Boruff JT; Cuijpers P; Gilbody S; Ioannidis JPA; Kloda LA; Patten SB; Shrier I; Ziegelste ...

Objectives: A previous individual participant data meta-analysis (IPDMA) identified differences in major depression classification rates between different diagnostic interviews, controlling for depressive symptoms on the basis of the Patient Health Questionnaire-9. We aimed to determine whether s ...

Article GUID: 31568624


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