Author(s): Nadeau BG; Marchant EG; Amir S; Mistlberger RE;

The forced swim test (FST) is a widely used animal model of depression and antidepressant drug screen. Rats are forced to swim on two test days in a restricted space from which there is no escape. On the first test day the rats attempt to escape and then become largely immobile; on the second test day the onset of immobility is more rapid. Immobility is s ...

Article GUID: 35065081