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A threshold LC-MS/MS method for 92 analytes in oral fluid collected with the Quantisal® device

Author(s): Desharnais B; Lajoie MJ; Laquerre J; Mireault P; Skinner CD;

A study of impaired driving rates in the province of Québec is currently planned following the legalization of recreational cannabis in Canada. Oral fluid (OF) samples are to be collected with a Quantisal® device and sent to the laboratory for analysis. In order to prepare for this project, a qualitative decision point analysis method monitoring for the p ...

Article GUID: 33035929


Qualitative threshold method validation and uncertainty evaluation: A theoretical framework and application to a 40 analytes liquid chromatography-tandem mass spectrometry method

Author(s): Camirand Lemyre F; Desharnais B; Laquerre J; Morel MA; Côté C; Mireault P; Skinner CD;

Qualitative methods hold an important place in drug testing, filling central needs in screening and analyses, among others, linked to per se legislation. Nevertheless, the bioanalytical method validation guidelines do not discuss this type of method or describe method validation procedures ill-adapted to qualitative methods. The output of qualitative meth ...

Article GUID: 32476284


Enzymatic assay for GHB determination in forensic matrices.

Author(s): Grenier V, Huppé G, Lamarche M, Mireault P

J Anal Toxicol. 2012 Sep;36(7):523-8 Authors: Grenier V, Huppé G, Lamarche M, Mireault P

Article GUID: 22722059


A case of fatal idiosyncratic reaction to the designer drug 3,4-methylenedioxypyrovalerone (MDPV) and review of the literature.

Author(s): Desharnais B, Dazé Y, Huppertz LM, Mireault P, Skinner CD

Forensic Sci Med Pathol. 2017 Sep;13(3):350-354 Authors: Desharnais B, Dazé Y, Huppertz LM, Mireault P, Skinner CD

Article GUID: 28668987


Challenges Related to Three Cases of Fatal Intoxication to Multiple Novel Synthetic Opioids.

Author(s): Garneau B, Desharnais B, Beauchamp-Doré A, Lavallée C, Mireault P, Lajeunesse A

J Anal Toxicol. 2019 Mar 30;: Authors: Garneau B, Desharnais B, Beauchamp-Doré A, Lavallée C, Mireault P, Lajeunesse A

Article GUID: 30927001


A Tool for Automatic Correction of Endogenous Concentrations: Application to BHB Analysis by LC-MS-MS and GC-MS

Author(s): Desharnais B; Lajoie MJ; Laquerre J; Savard S; Mireault P; Skinner CD;

Several substances relevant for forensic toxicology purposes have an endogenous presence in biological matrices: beta-hydroxybutyric acid (BHB), gamma-hydroxybutyric acid (GHB), steroids and human insulin, to name only a few. The presence of significant amounts of these endogenous substances in the biological matrix used to prepare calibration standards a ...

Article GUID: 31141151


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