Author(s): Golden CK; Kazmirchuk TDD; McNally EK; El Eissawi M; Gokbayrak ZD; Richard JD; Brett CL;
Diverse physiology relies on receptor and transporter protein down-regulation and degradation mediated by ESCRTs. Loss-of-function mutations in human ESCRT genes linked to cancers and neurological disorders are thought to block this process. However, when homologous mutations are introduced into model organisms, cells thrive and degradation persists, sugg ...
Article GUID: 36215320
Author(s): Karim MA, McNally EK, Samyn DR, Mattie S, Brett CL
Dev Cell. 2018 10 08;47(1):80-97.e6 Authors: Karim MA, McNally EK, Samyn DR, Mattie S, Brett CL
Article GUID: 30269949
Author(s): McNally EK, Brett CL
Nat Commun. 2018 12 18;9(1):5358 Authors: McNally EK, Brett CL
Article GUID: 30560896
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