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Functional and structural characterization of an IclR family transcription factor for the development of dicarboxylic acid biosensors

Author(s): Pham C; Nasr MA; Skarina T; Di Leo R; Kwan DH; Martin VJJ; Stogios PJ; Mahadevan R; Savchenko A;

Prokaryotic transcription factors (TFs) regulate gene expression in response to small molecules, thus representing promising candidates as versatile small molecule-detecting biosensors valuable for synthetic biology applications. The engineering of such biosensors requires thorough in vitro and i ...

Article GUID: 38696354


Advancing Undergraduate Synthetic Biology Education: Insights from a Canadian iGEM Student Perspective

Author(s): Diep P; Boucinha A; Kell BJ; Yeung BA; Chen XA; Tsyplenkov D; Serra D; Escobar A; Gnanapragasam A; Emond CA; Sajtovich VA; Mahadevan R; Kilkenny DM; Gini-Newman G; Kaern M; Ingalls B;

The last two decades have seen vigorous activity in synthetic biology research and ever-increasing applications of its technologies. However, pedagogical research pertaining to teaching synthetic biology is scarce, especially when compared to other science and engineering disciplines. Within Cana ...

Article GUID: 34237221


Metabolic engineering of a tyrosine-overproducing yeast platform using targeted metabolomics.

Author(s): Gold ND, Gowen CM, Lussier FX, Cautha SC, Mahadevan R, Martin VJ

Microb Cell Fact. 2015 May 28;14:73 Authors: Gold ND, Gowen CM, Lussier FX, Cautha SC, Mahadevan R, Martin VJ

Article GUID: 26016674


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