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Crowd Counting Using Meta-Test-Time Adaptation

Author(s): Ma C; Neri F; Gu L; Wang Z; Wang J; Qing A; Wang Y;

Machine learning algorithms are commonly used for quickly and efficiently counting people from a crowd. Test-time adaptation methods for crowd counting adjust model parameters and employ additional data augmentation to better adapt the model to the specific conditions encountered during testing. The majority of current studies concentrate on unsupervised ...

Article GUID: 39252679


Revisiting Homochiral versus Heterochiral Interactions through a Long Detective Story of a Useful Azobis-Nitrile and Puzzling Racemate

Author(s): García de la Concepción J; Flores-Jiménez M; Cuccia LA; Light ME; Viedma C; Cintas P;

This paper documents and reinvestigates the solid-state and crystal structures of 4,4'-azobis-4-cyanopentanoic acid (ACPA), a water-soluble azobis-nitrile of immense utility as a radical initiator in living polymerizations and a labile mechanophore that can be embedded within long polymer chains to undergo selective scission under mechanical activatio ...

Article GUID: 37547876


On the Origin of Sugar Handedness: Facts, Hypotheses and Missing Links-A Review

Author(s): Martínez RF; Cuccia LA; Viedma C; Cintas P;

By paraphrasing one of Kipling's most amazing short stories (How the Leopard Got His Spots), this article could be entitled "How Sugars Became Homochiral". Obviously, we have no answer to this still unsolved mystery, and this perspective simply brings recent models, experiments and hypotheses into the homochiral homogeneity of sugars on earth. We shal ...

Article GUID: 35796896


Empowering Melatonin Therapeutics with Drosophila Models

Author(s): Millet-Boureima C; Ennis CC; Jamison J; McSweeney S; Park A; Gamberi C;

Melatonin functions as a central regulator of cell and organismal function as well as a neurohormone involved in several processes, e.g., the regulation of the circadian rhythm, sleep, aging, oxidative response, and more. As such, it holds immense pharmacological potential. Receptor-mediated melatonin function mainly occurs through MT1 and MT2, conserved ...

Article GUID: 34698120


The Biology of Vasopressin.

Author(s): Sparapani S, Millet-Boureima C, Oliver J, Mu K, Hadavi P, Kalostian T, Ali N, Avelar CM, Bardies M, Barrow B, Benedikt M, Biancardi G, Bindra R, Bui L, Chihab Z, Cossitt A, Costa J, Daigneault T, Dault J, Davidson I, Dias J, Dufour E, El ...

Vasopressins are evolutionarily conserved peptide hormones. Mammalian vasopressin functions systemically as an antidiuretic and regulator of blood and cardiac flow essential for adapting to terrestrial environments. Moreover, vasopressin acts centrally as a neurohormone involved in social and par ...

Article GUID: 33477721


Cyst Reduction by Melatonin in a Novel Drosophila Model of Polycystic Kidney Disease.

Author(s): Millet-Boureima C; Rozencwaig R; Polyak F; Gamberi C;

Autosomal dominant polycystic kidney disease (ADPKD) causes progressive cystic degeneration of the renal tubules, the nephrons, eventually severely compromising kidney function. ADPKD is incurable, with half of the patients eventually needing renal replacement. Treatments for ADPKD patients are limited and new effective therapeutics are needed. Melatonin, ...

Article GUID: 33238462


Drug discovery and chemical probing in Drosophila.

Author(s): Millet-Boureima C, Selber-Hnatiw S, Gamberi C

Genome. 2020 Jun 18;: Authors: Millet-Boureima C, Selber-Hnatiw S, Gamberi C

Article GUID: 32551911


Pasteur made simple - mechanochemical transformation of racemic amino acid crystals into racemic conglomerate crystals.

Author(s): Viedma C, Lennox C, Cuccia LA, Cintas P, Ortiz JE

Chem Commun (Camb). 2020 Mar 23;: Authors: Viedma C, Lennox C, Cuccia LA, Cintas P, Ortiz JE

Article GUID: 32202285


Cyst Reduction in a Polycystic Kidney Disease Drosophila Model Using Smac Mimics.

Author(s): Millet-Boureima C, Chingle R, Lubell WD, Gamberi C

Biomedicines. 2019 Oct 18;7(4): Authors: Millet-Boureima C, Chingle R, Lubell WD, Gamberi C

Article GUID: 31635379


Modeling Renal Disease "On the Fly".

Author(s): Millet-Boureima C, Porras Marroquin J, Gamberi C

Biomed Res Int. 2018;2018:5697436 Authors: Millet-Boureima C, Porras Marroquin J, Gamberi C

Article GUID: 29955604


Oriented attachment by enantioselective facet recognition in millimeter-sized gypsum crystals.

Author(s): Viedma C, Cuccia LA, McTaggart A, Kahr B, Martin AT, McBride JM, Cintas P

Chem Commun (Camb). 2016 Sep 22;52(78):11673-11676 Authors: Viedma C, Cuccia LA, McTaggart A, Kahr B, Martin AT, McBride JM, Cintas P

Article GUID: 27722508


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