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Alternative Oxidase: From Molecule and Function to Future Inhibitors

Author(s): Li J; Yang S; Wu Y; Wang R; Liu Y; Liu J; Ye Z; Tang R; Whiteway M; Lv Q; Yan L;

In the respiratory chain of the majority of aerobic organisms, the enzyme alternative oxidase (AOX) functions as the terminal oxidase and has important roles in maintaining metabolic and signaling homeostasis in mitochondria. AOX endows the respiratory system with flexibility in the coupling among the carbon metabolism pathway, electron transport chain (E ...

Article GUID: 38524433


TRAPPC6B biallelic variants cause a neurodevelopmental disorder with TRAPP II and trafficking disruptions

Author(s): Almousa H; Lewis SA; Bakhtiari S; Nordlie SH; Pagnozzi A; Magee H; Efthymiou S; Heim JA; Cornejo P; Zaki MS; Anwar N; Maqbool S; Rahman F; Neilson DE; Vemuri A; Jin SC; Yang XR; Heidari A; van Gassen K; Trimouille A; Thauvin-Robinet C; L ...

Highly conserved transport protein particle (TRAPP) complexes regulate subcellular trafficking pathways. Accurate protein trafficking has been increasingly recognized to be critically important for normal development, particularly in the nervous system. Variants in most TRAPP complex subunits hav ...

Article GUID: 37713627


Effect of COVID-19 on non-performing loans in China

Author(s): Kryzanowski L; Liu J; Zhang J;

We examine the resilience of Chinese banks during the COVID-19 pandemic by investigating non-performing loan (NPL) ratios. We find that despite the reduction in the growth rate of total bank lending, bank NPL ratios significantly increase during the COVID-19 crisis. Banks with high-quality capital are more effective in controlling their NPL ratios during ...

Article GUID: 36164498


Investigating the Accumulation of Submicron Phase-Change Droplets in Tumors.

Author(s): Helfield BL, Yoo K, Liu J, Williams R, Sheeran PS, Goertz DE, Burns PN

Ultrasound Med Biol. 2020 Jul 27;: Authors: Helfield BL, Yoo K, Liu J, Williams R, Sheeran PS, Goertz DE, Burns PN

Article GUID: 32732167


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